| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Bossolan, Grasiela | |
| dc.creator | Trindade, Cleide E. P. | |
| dc.creator | Barreiros, Rodrigo Crespo | |
| dc.date | 2014-05-20T13:37:51Z | |
| dc.date | 2016-10-25T16:54:21Z | |
| dc.date | 2014-05-20T13:37:51Z | |
| dc.date | 2016-10-25T16:54:21Z | |
| dc.date | 2007-01-01 | |
| dc.date.accessioned | 2017-04-05T20:34:11Z | |
| dc.date.available | 2017-04-05T20:34:11Z | |
| dc.identifier | Neonatology. Basel: Karger, v. 91, n. 2, p. 121-126, 2007. | |
| dc.identifier | 1661-7800 | |
| dc.identifier | http://hdl.handle.net/11449/13117 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/13117 | |
| dc.identifier | 10.1159/000097129 | |
| dc.identifier | WOS:000244967400007 | |
| dc.identifier | http://dx.doi.org/10.1159/000097129 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/860544 | |
| dc.description | Background: Although galactose is an important component in human lactose, there are few reports of its role in the newborn metabolism. Objective: To determine the relationship of blood galactose and glucose levels in mothers, cord blood, and breast-fed full-term newborn infants. Methods: Maternal and cord vein blood samples were obtained from 27 pregnant women at delivery, and from their breastfed, full-term newborns 48 h later. Galactose and glucose were determined by HPLC. Statistical analysis used ANOVA and Pearson correlation with p < 0.05. Results: Maternal galactose concentrations (0.08 +/- 0.03 mmol/l) were similar to cord blood galactose (0.07 +/- 0.03 mmol/l; p = 0.129). However, newborn blood galactose (0.05 +/- 0.02 mmol/l) was significantly lower than both cord (p = 0.042) and maternal blood (p = 0.002). Maternal blood glucose levels (4.72 +/- 0.86 mmol/l) were higher than cord blood (3.98 +/- 0.57 mmol/l; p < 0.001), and cord blood concentrations were higher than newborn blood levels (3.00 +/- 0.56 mmol/l; p < 0.001); all values expressed as mean +/- SD. Significant correlation was only seen between maternal and cord blood galactose levels (r = 0.67; p < 0.001) and glucose levels (r = 0.38; p = 0.047). Conclusion: the association and similarity between maternal and cord blood galactose levels suggest that the fetus is dependent on maternal galactose. In contrast, the lower galactose levels in newborn infants and a lack of association between both suggest self-regulation and a dependence on galactose ingestion. Copyright (c) 2007 S. Karger AG, Basel. | |
| dc.language | eng | |
| dc.publisher | Karger | |
| dc.relation | Neonatology | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | galactose | |
| dc.subject | glucose | |
| dc.subject | newborn infant | |
| dc.subject | cord blood | |
| dc.subject | full-term infant | |
| dc.title | Blood galactose and glucose levels in mothers, cord blood, and 48-hour-old breast-fed full-term infants | |
| dc.type | Otro | |
