KSHV genotypes A and C are more frequent in Kaposi sarcoma lesions from Brazilian patients with and without HIV infection, respectively

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSilva, Suzane Ramos de
dc.creatorSilva, Ana Paula Ferraz da
dc.creatorBacchi, Maura Moscardi
dc.creatorBacchi, Carlos Eduardo
dc.creatorOliveira, Deilson Elgui de
dc.date2014-05-20T13:37:37Z
dc.date2016-10-25T16:54:15Z
dc.date2014-05-20T13:37:37Z
dc.date2016-10-25T16:54:15Z
dc.date2011-02-01
dc.date.accessioned2017-04-05T20:33:51Z
dc.date.available2017-04-05T20:33:51Z
dc.identifierCancer Letters. Clare: Elsevier B.V., v. 301, n. 1, p. 85-94, 2011.
dc.identifier0304-3835
dc.identifierhttp://hdl.handle.net/11449/13043
dc.identifierhttp://acervodigital.unesp.br/handle/11449/13043
dc.identifier10.1016/j.canlet.2010.10.011
dc.identifierWOS:000287108900010
dc.identifierhttp://dx.doi.org/10.1016/j.canlet.2010.10.011
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/860504
dc.descriptionThe present study aimed to evaluate the frequency of KSHV genotypes isolated from Kaposi sarcoma (KS) lesions in patients from Brazil. Fifty KS cases were evaluated. The most frequently detected viral genotypes were A (50.0%) and C (48.0%); the B genotype was isolated only in one case (2.0%). Noteworthy, there was a significant predominance of A genotypes in KS lesions from HIV-positive patients, whereas C genotypes were found mostly in the HIV-negative setting. This finding supports the hypothesis that distinct KSHV genotypes have a non-random distribution in KS, which might be attributable to unique biological properties. (C) 2010 Elsevier B.V. All rights reserved.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.languageeng
dc.publisherElsevier B.V.
dc.relationCancer Letters
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectKSHV
dc.subjectHHV-8
dc.subjectKaposi sarcoma
dc.subjectViral genotyping
dc.titleKSHV genotypes A and C are more frequent in Kaposi sarcoma lesions from Brazilian patients with and without HIV infection, respectively
dc.typeOtro


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