Immunoexpression of transforming growth factor beta and interferon gamma in radicular and dentigerous cysts

dc.creatorMoraes, Maiara de
dc.creatorRocha-Neto, Pedro Carlos da
dc.creatorMatos, Felipe Rodrigues de
dc.creatorLopes, Maria Luiza Diniz de Sousa
dc.creatorAzevedo, Paulo Roberto Medeiros de
dc.creatorCosta, Antonio de Lisboa Lopes
dc.date2023-03-24T19:20:07Z
dc.date2023-03-24T19:20:07Z
dc.date2014-09
dc.date.accessioned2023-09-04T13:55:13Z
dc.date.available2023-09-04T13:55:13Z
dc.identifierMORAES, Maiara de. et al. Immunoexpression of transforming growth factor beta and Interferon gamma in radicular and dentigerous cysts. Journal of Endodontics, v. 40, p. 1293-1297, 2014. Disponível em: http://www.sciencedirect.com/science/article/pii/S0099239914000697. Acesso em: 08 dez. 2017.
dc.identifierhttps://repositorio.ufrn.br/handle/123456789/51950
dc.identifierhttps://doi.org/10.1016/j.joen.2014.01.010
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8603436
dc.descriptionIntroduction: The aim of this study was to evaluate and compare the immunohistochemical expression of transforming growing factor beta (TGF-b) and interferon gamma (IFN-g) between radicular cysts (RCs) and dentigerous cysts (DCs). Methods: Twenty RCs and DCs were selected for analysis of the immunoexpression of TGF-b and IFN-g in the epithelium and capsule. Results: The cell reactivity of TGF-b and IFN-g in the lining epithelium and capsule of RCs showed no significant differences when compared with DCs (P > .05). There was a tendency of a higher expression of TGF-b in the capsule of DCs. Conclusions: Our results showed the presence of TGF-b and IFN-g in RCs and DCs, supporting the hypothesis that both participate in the development of these lesions, where IFN-g usually plays a role in bone resorption, which is counterbalanced by the osteoprotective activity performed by TGF-b.
dc.languageen
dc.publisherElsevier
dc.rightsAcesso Aberto
dc.subjectDentigerous cyst
dc.subjectImmunohistochemistry
dc.subjectInterferon gamma
dc.subjectRadicular cyst
dc.subjectTransforming growth factors
dc.titleImmunoexpression of transforming growth factor beta and interferon gamma in radicular and dentigerous cysts
dc.typearticle


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