| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Ihlaseh, Shadia Muhammad | |
| dc.creator | Oliveira, Maria Luiza Cotrim Sartor de | |
| dc.creator | Teran, Elizabeth | |
| dc.creator | Camargo, João Lauro Viana de | |
| dc.creator | Barbisan, Luis Fernando | |
| dc.date | 2014-05-20T13:36:59Z | |
| dc.date | 2016-10-25T16:53:51Z | |
| dc.date | 2014-05-20T13:36:59Z | |
| dc.date | 2016-10-25T16:53:51Z | |
| dc.date | 2006-11-01 | |
| dc.date.accessioned | 2017-04-05T20:32:22Z | |
| dc.date.available | 2017-04-05T20:32:22Z | |
| dc.identifier | World Journal of Urology. New York: Springer, v. 24, n. 5, p. 591-596, 2006. | |
| dc.identifier | 0724-4983 | |
| dc.identifier | http://hdl.handle.net/11449/12757 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/12757 | |
| dc.identifier | 10.1007/s00345-006-0108-9 | |
| dc.identifier | WOS:000242154500014 | |
| dc.identifier | http://dx.doi.org/10.1007/s00345-006-0108-9 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/860310 | |
| dc.description | The modifying potential of ginger on the development of preneoplasia and tumors in the male Wistar rat urinary bladder was investigated in a 36-week-long initiation-promotion assay for chemical carcinogenesis. Groups G1 to G3 were given 0.05% N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) in drinking water for 5 weeks and a 3% uracil meal for the subsequent 3 weeks. Groups G4 and G5 were treated with 3% uracil only for the same period. After these steps, groups G2, and G3 and G4 were fed for 26 weeks a ginger extract mixed at 0.5 and 1.0% in a basal diet, respectively. Thirty six weeks after the beginning of the experiment all rats were killed. The multiplicity of urothelial lesions (hyperplasia and neoplasia) was significantly lower (P = 0.013) in group G3 than in groups G1 and G2. The results suggest that 1.0% ginger meal exerts a protective effect on the post-initiation stage of rat chemically-induced urothelial carcinogenesis. | |
| dc.language | eng | |
| dc.publisher | Springer | |
| dc.relation | World Journal of Urology | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | ginger | |
| dc.subject | chemoprevention | |
| dc.subject | rat urothelial carcinogenesis | |
| dc.title | Chemopreventive property of dietary ginger in rat urinary bladder chemical carcinogenesis | |
| dc.type | Otro | |
