Risk factors for Hospital-Acquired Pneumonia in nonventilated adults

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorFortaleza, Carlos Magno Castelo Branco
dc.creatorAbati, Paulo Afonso Martins
dc.creatorBatista, Márcia Regina
dc.creatorDias, Adriano
dc.date2014-05-20T13:34:41Z
dc.date2014-05-20T13:34:41Z
dc.date2009-08-01
dc.date.accessioned2017-04-05T20:26:49Z
dc.date.available2017-04-05T20:26:49Z
dc.identifierBrazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 13, n. 4, p. 284-288, 2009.
dc.identifier1413-8670
dc.identifierhttp://hdl.handle.net/11449/11904
dc.identifier10.1590/S1413-86702009000400009
dc.identifierS1413-86702009000400009
dc.identifierWOS:000275592800009
dc.identifierS1413-86702009000400009.pdf
dc.identifierhttp://dx.doi.org/10.1590/S1413-86702009000400009
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/859602
dc.descriptionAlthough most recent publications focus on Ventilator-associated Pneumonia, Non-Ventilator-associated Hospital-acquired pneumonia (NVHAP) is still worrisome. We studied risk factors for NVHAP among patients admitted to a small teaching hospital. Sixty-six NVHAP case patients and 66 controls admitted to the hospital from November 2005 through November 2006 were enrolled in a case-control study. Variables under investigation included: demographic characteristics, comorbidities, procedures, invasive devices and use of medications (Sedatives, Antacids, Steroids and Antimicrobials). Univariate and multivariable analysis (hierarchical models of logistic regression) were performed. The incidence of NVHAP in our hospital was 0.68% (1.02 per 1,000 patients-day). Results from multivariable analysis identified risk factors for NVHAP: age (Odds Ratio[OR]=1.03, 95% Confidence Interval[CI]=1.01-1.05, p=0.002), use of Antacids (OR=5.29, 95%CI=1.89-4.79, p=0.001) and Central Nervous System disease (OR=3.13, 95%CI=1.24-7.93, p=0.02). Although our findings are coherent with previous reports, the association of Antacids with NVHAP recalls a controversial issue in the physiopathology of Hospital-Acquired Pneumonia, with possible implications for preventive strategies.
dc.languageeng
dc.publisherBrazilian Society of Infectious Diseases
dc.relationBrazilian Journal of Infectious Diseases
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHospital acquired pneumonia
dc.subjectnon-ventilator associated pneumonia
dc.subjectrisk factors
dc.titleRisk factors for Hospital-Acquired Pneumonia in nonventilated adults
dc.typeOtro


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