dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorHorta, M. L.
dc.creatorVianna, PTG
dc.date2014-05-20T13:31:53Z
dc.date2016-10-25T16:50:23Z
dc.date2014-05-20T13:31:53Z
dc.date2016-10-25T16:50:23Z
dc.date2003-08-01
dc.date.accessioned2017-04-05T20:19:53Z
dc.date.available2017-04-05T20:19:53Z
dc.identifierBritish Journal of Anaesthesia. Oxford: Oxford Univ Press, v. 91, n. 2, p. 287-289, 2003.
dc.identifier0007-0912
dc.identifierhttp://hdl.handle.net/11449/10865
dc.identifierhttp://acervodigital.unesp.br/handle/11449/10865
dc.identifier10.1093/bja/aeg164
dc.identifierWOS:000184639300021
dc.identifierhttp://dx.doi.org/10.1093/bja/aeg164
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/858703
dc.descriptionBackground. This double-blind study was undertaken to determine whether alizapride inhibits spinal morphine-induced pruritus.Methods. Eighty-four patients undergoing Caesarean section under spinal anaesthesia (100 mg of hyperbaric lidocaine 5% plus morphine 0.2 mg) were randomly allocated to one of two groups. just after birth, alizapride-50 mg (alizapride group) or metoclopramide 10 mg (metoclopramide group) were injected i.v. Patients were assessed after surgery for pruritus (absent, mild, moderate or severe) or other untoward symptoms.Results. In the metoclopramide group, pruritus was absent in 5 (12%) patients, mild in 23 (55%), moderate in 11 (26%), and severe in 3 (7%), while in the alizapride group, these incidences were, respectively, 5 (12%), 33 (79%), 4 (10%), and 0 (P=0.045, chi(2)-test). There was no difference in the incidence of side-effects, which were all minor.Conclusions. Alizapride reduced the severity of morphine-induced pruritus.
dc.languageeng
dc.publisherOxford University Press
dc.relationBritish Journal of Anaesthesia
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectanaesthesia, obstetric
dc.subjectanalgesics opioid, morphine
dc.subjectcomplications, pruritus
dc.subjectpharmacology, alizapride
dc.titleEffect of intravenous alizapride on spinal morphine-induced pruritus
dc.typeOtro


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