dc.contributor | Universidade Estadual Paulista (UNESP) | |
dc.creator | Chung, Man-Chin | |
dc.creator | Silva, Antonio Távora de Albuquerque | |
dc.creator | Castro, Lúcia Fioravanti | |
dc.creator | Güido, Rafael Victório Carvalho | |
dc.creator | Nassute, José Carlos | |
dc.creator | Ferreira, Elizabeth Igne | |
dc.date | 2014-05-20T13:25:17Z | |
dc.date | 2014-05-20T13:25:17Z | |
dc.date | 2005-06-01 | |
dc.date.accessioned | 2017-04-05T20:02:42Z | |
dc.date.available | 2017-04-05T20:02:42Z | |
dc.identifier | Revista Brasileira de Ciências Farmacêuticas. Divisão de Biblioteca e Documentação do Conjunto das Químicas da Universidade de São Paulo, v. 41, n. 2, p. 155-180, 2005. | |
dc.identifier | 1516-9332 | |
dc.identifier | http://hdl.handle.net/11449/8000 | |
dc.identifier | 10.1590/S1516-93322005000200004 | |
dc.identifier | S1516-93322005000200004 | |
dc.identifier | S1516-93322005000200004.pdf | |
dc.identifier | 2-s2.0-26244457606 | |
dc.identifier | http://dx.doi.org/10.1590/S1516-93322005000200004 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/856504 | |
dc.description | O processo de modificação molecular denominado latenciação é revisto, apresentando formas avançadas no transporte de fármacos, utilizando macromoléculas como transportadores e sistemas de liberação sítio-específica como: CDS (Chemical Delivery System), ADEPT (Antibody-Directed Enzyme Prodrug Therapy), GDEPT/VDEPT (Gene-Directed Enzyme Prodrug Therapy/Vírus-Directed Enzyme Prodrug Therapy), ODDS (Osteotropic Drug Delivery System), PDEPT (Polymer-Directed Enzyme Prodrug Therapy), PELT (Polymer-Enzyme Liposome Therapy) e LEAPT (Lectin-Directed Enzyme-Activated Prodrug Therapy). | |
dc.description | This is a review about the molecular modification process, called latentiation, or prodrug design, focusing the progress in the prodrug approach using macromolecules as carriers and drug target systems as: PDEPT ( Polymer-Directed Enzyme Prodrug Therapy); PELT (Polymer-Enzyme Liposome Therapy); CDS (Chemical Delivery System); ADEPT(Antibody-Directed Enzyme Prodrug Therapy; GDEPT/VDEPT (Gene-Directed Enzyme Prodrug Therapy/Virus-Directed Enzyme Prodrug Therapy and ODDS (Osteotropic Drug Delivery System) and LEAPT (Lectin-Directed Enzyme-Activated Prodrug Therapy). | |
dc.language | por | |
dc.publisher | Divisão de Biblioteca e Documentação do Conjunto das Químicas da Universidade de São Paulo | |
dc.relation | Revista Brasileira de Ciências Farmacêuticas | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Latenciação | |
dc.subject | Pró-fármacos | |
dc.subject | Transportadores macromoleculares | |
dc.subject | Sistemas de liberação específica | |
dc.subject | Latentiation | |
dc.subject | Prodrug design | |
dc.subject | Macromolecular carriers | |
dc.subject | Drug target systems | |
dc.title | Latenciação e formas avançadas de transporte de fármacos | |
dc.type | Otro | |