dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorMasquio Fiorentino, Flavia Angelica
dc.creatorCorrea, Marcos Antonio
dc.creatorSalgado, Hérida Regina Nunes
dc.date2014-05-20T13:24:52Z
dc.date2016-10-25T16:45:32Z
dc.date2014-05-20T13:24:52Z
dc.date2016-10-25T16:45:32Z
dc.date2010-01-01
dc.date.accessioned2017-04-05T20:01:35Z
dc.date.available2017-04-05T20:01:35Z
dc.identifierCritical Reviews In Analytical Chemistry. Philadelphia: Taylor & Francis Inc, v. 40, n. 2, p. 89-101, 2010.
dc.identifier1040-8347
dc.identifierhttp://hdl.handle.net/11449/7834
dc.identifierhttp://acervodigital.unesp.br/handle/11449/7834
dc.identifier10.1080/10408340903232020
dc.identifierWOS:000277518600003
dc.identifierhttp://dx.doi.org/10.1080/10408340903232020
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/856368
dc.descriptionChlorhexidine is a type of antiseptic belonging to biguanidic group and it is large, used in dentistry, human, and veterinary medicine because it is active against Gram-positive and Gram-negative microorganisms. It can be incorporated in several types of preparations and for this reason are necessary effective analytical procedures for quality control and pharmacodynamic and pharmacokinetic studies. Chlorhexidine can be analyzed by many types of assays, however the HPLC is the most used method. In this review, various methods to analyze chlorhexidine including spectrometry, chromatography, colorimetric reaction, solid phase extraction, and capillary electrophoresis are presented and the application of these methods for the determination of chlorhexidine in biological fluids and formulations are discussed.
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherTaylor & Francis Inc
dc.relationCritical Reviews in Analytical Chemistry
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectreview
dc.subjectchlorhexidine
dc.subjectmethods of analysis
dc.titleAnalytical Methods for the Determination of Chlorhexidine: A Review
dc.typeOtro


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