Green ultrasound-assisted extraction of lichen substances from Hypotrachyna cirrhata. Ethyl lactate, a better extracting agent than methanol toxic organic solvent?

dc.creatorSepulveda, Beatriz
dc.creatorBenites, Derin
dc.creatorAlbornoz, Laura
dc.creatorSimirgiotis, Mario
dc.creatorCastro, Olivio
dc.creatorGarcia-Beltran, Olimpo
dc.creatorAreche, Carlos
dc.date2022-08-30T22:04:09Z
dc.date2022-08-30T22:04:09Z
dc.date2021-07-28
dc.date.accessioned2023-08-31T19:24:53Z
dc.date.available2023-08-31T19:24:53Z
dc.identifierSepulveda B, Benites D, Albornoz L, Simirgiotis M, Castro O, Garcia-Beltran O, Areche C. Green ultrasound-assisted extraction of lichen substances from Hypotrachyna cirrhata. Ethyl lactate, a better extracting agent than methanol toxic organic solvent? Nat Prod Res. 2021 Jul 28:1-5. doi: 10.1080/14786419.2021.1956922. Epub ahead of print. PMID: 34319194.
dc.identifier1478-6419
dc.identifierhttps://pubmed.ncbi.nlm.nih.gov/34319194/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8558105
dc.descriptionFor the first time, we report a green extraction of lichen substances assisted by high power ultrasounds from Hypotrachyna cirrhata using ethyl lactate. This sustainable alternative was comparable, both in isolation and detection of lichen substances, to methanol. In the metabolomic analysis, a total of 77 lichen substances were detected comprising depsides, depsidones, dibenzofurans, organic acids, and lipids. Although the UHPLC/ESI/MS profiles were similar, the antioxidant activity was higher for the ethyl lactate extract. Ethyl lactate can replace toxic organic solvents, such as methanol, in order to provide more sustainable green chemistry methods.
dc.descriptionUniversidad de Ibagu?
dc.languageen
dc.publisherNatural Product Research
dc.subjectAlternative solvents
dc.subjectAntioxidants
dc.subjectGreen chemistry
dc.subjectHypotrachyna
dc.subjectLC/MS
dc.subjectLichens
dc.subjectUltrasound
dc.titleGreen ultrasound-assisted extraction of lichen substances from Hypotrachyna cirrhata. Ethyl lactate, a better extracting agent than methanol toxic organic solvent?
dc.typeArticle


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