Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor

dc.creatorHoushmandi, S.S.
dc.creatorSurace, Ezequiel Ignacio
dc.creatorZhang, H.B.
dc.creatorFuller, G.N.
dc.creatorGutmann, D.H.
dc.date2006-11
dc.date.accessioned2023-08-31T00:42:17Z
dc.date.available2023-08-31T00:42:17Z
dc.identifierhttp://hdl.handle.net/11336/39064
dc.identifierHoushmandi, S.S.; Surace, Ezequiel Ignacio; Zhang, H.B.; Fuller, G.N.; Gutmann, D.H.; Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor; Lippincott Williams; Neurology; 67; 10; 11-2006; 1863-1866
dc.identifier0028-3878
dc.identifier1526-632X
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8543697
dc.descriptionTumor suppressor in lung cancer-1 (TSLC1) loss is common in many human cancers, including meningioma. In this study, we demonstrate that TSLC1 protein and RNA expression is lost in 60% to 65% of high-grade gliomas, and that TSLC1 reintroduction into glioma cells results in growth suppression. Moreover, Tslc1 loss in mice results in increased astrocyte proliferation in vivo and in vitro. These data indicate that TSLC1 functions as a glioma tumor suppressor. ©2006AAN Enterprises, Inc.
dc.descriptionFil: Houshmandi, S.S.. Washington University in St. Louis; Estados Unidos
dc.descriptionFil: Surace, Ezequiel Ignacio. Washington University in St. Louis; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
dc.descriptionFil: Zhang, H.B.. Washington University in St. Louis; Estados Unidos
dc.descriptionFil: Fuller, G.N.. University of Texas; Estados Unidos
dc.descriptionFil: Gutmann, D.H.. Washington University in St. Louis; Estados Unidos
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherLippincott Williams
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://n.neurology.org/content/67/10/1863.long
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1212/01.wnl.0000244472.56198.84
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subjectLung Cancer
dc.subjectTumor Suppressor
dc.subjecthttps://purl.org/becyt/ford/1.6
dc.subjecthttps://purl.org/becyt/ford/1
dc.titleTumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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