Effect of Fe overload on ascorbyl radical steady state concentration in rat brain

dc.contributorKumar Chittoria, Ravi
dc.creatorPiloni, Natacha Estefanía
dc.creatorPuntarulo, Susana Ángela
dc.date2022
dc.date.accessioned2023-08-31T00:35:25Z
dc.date.available2023-08-31T00:35:25Z
dc.identifierhttp://hdl.handle.net/11336/204474
dc.identifierPiloni, Natacha Estefanía; Puntarulo, Susana Ángela; Effect of Fe overload on ascorbyl radical steady state concentration in rat brain; B P International; 4; 2022; 1-17
dc.identifier978-93-5547-448-3
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8543587
dc.descriptionThe one-electron oxidation of ascorbate produces the ascorbyl radical (A), that has beenproposed as a marker of oxidative stress either in vitro, or in vivo in numerous systems. Theapplication of a simple kinetic analysis allowed us to estimate the steady state concentration of A.These data were successfully compared to experimental values obtained using ElectronParamagnetic Resonance (EPR) in rat brain under physiological conditions and the response tostress due to sub-chronic Fe overload. The main objective of this chapter is to further explore theinformation presented in a previously published manuscript employing a simple kinetic modeldeveloped to estimate A steady state concentration to other Fe-dependent oxidative conditions inrat brain.
dc.descriptionFil: Piloni, Natacha Estefanía. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
dc.descriptionFil: Puntarulo, Susana Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherB P International
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.bookpi.org/bookstore/product/issues-and-developments-in-medicine-and-medical-research-vol-4/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subjectASCORBYL RADICAL
dc.subjectBRAIN
dc.subjectIRON OVERLOAD
dc.subjectKINETIC MODEL
dc.subjecthttps://purl.org/becyt/ford/1.6
dc.subjecthttps://purl.org/becyt/ford/1
dc.titleEffect of Fe overload on ascorbyl radical steady state concentration in rat brain
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeinfo:eu-repo/semantics/bookPart
dc.typeinfo:ar-repo/semantics/parte de libro


Este ítem pertenece a la siguiente institución