Omicron waves in Argentina: dynamics of SARS-CoV-2 lineages BA.1, BA.2 and the emerging BA.2.12.1 and BA.4/BA.5

dc.creatorTorres, Carolina
dc.creatorNabaes Jodar, Mercedes
dc.creatorAcuña, Dolores
dc.creatorZambrana Montaño, Romina Micaela
dc.creatorCulasso, Andrés Carlos Alberto
dc.creatorAmadio, Ariel Fernando
dc.creatorAulicino, Paula
dc.creatorCeballos, Santiago
dc.creatorCacciabue, Marco
dc.creatorDebat, Humberto
dc.creatorDus Santos, María José
dc.creatorEberhardt, María Florencia
dc.creatorEspul, Carlos
dc.creatorFay, Fabián
dc.creatorFernández, María Ailén
dc.creatorFernández, Franco
dc.creatorFernandez Muñoz, Juan Manuel
dc.creatorFerrini, Florencia
dc.creatorGallego, Fernando
dc.creatorGiri, Adriana Angélica
dc.creatorCerri, Agustina
dc.creatorBolatti, Elisa María
dc.creatorGismondi, María Ines
dc.creatorGoya, Stephanie
dc.creatorGramundi, Iván
dc.creatorIrazoqui, José Matías
dc.creatorKönig, Guido Alberto
dc.creatorLeiva, Viviana
dc.creatorLucero, Horacio
dc.creatorMarquez, Nathalie
dc.creatorNardi, Cristina
dc.creatorOrtiz, Belén
dc.creatorPianciola, Luis
dc.creatorPintos, Carolina Beatriz
dc.creatorPuebla, Andrea Fabiana
dc.creatorRastellini, Carolina Victoria
dc.creatorRojas, Alejandro Ezequiel
dc.creatorSfalcin, Javier
dc.creatorSuárez, Ariel
dc.creatorTittarelli, Estefanía
dc.creatorToro, Rosana
dc.creatorVillanova, Gabriela Vanina
dc.creatorZiehm, María Cecilia
dc.creatorZimmermann, María Carla
dc.creatorZunino, Sebastián
dc.creatorProyecto PAIS Working Group
dc.creatorValinotto, Laura
dc.creatorViegas, Mariana
dc.date2023-04-03T15:25:03Z
dc.date2023-04-03T15:25:03Z
dc.date2023-01-22
dc.date2023-04-03T15:25:03Z
dc.date2023-04-03T15:25:03Z
dc.date2023-01-22
dc.date.accessioned2023-08-30T21:18:35Z
dc.date.available2023-08-30T21:18:35Z
dc.identifier1999-4915
dc.identifierhttp://hdl.handle.net/2133/25429
dc.identifierhttp://hdl.handle.net/2133/25429
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8542268
dc.descriptionThe COVID-19 pandemic has lately been driven by Omicron. This work aimed to study the dynamics of SARS-CoV-2 Omicron lineages during the third and fourth waves of COVID-19 in Argentina. Molecular surveillance was performed on 3431 samples from Argentina, between EW44/2021 and EW31/2022. Sequencing, phylogenetic and phylodynamic analyses were performed. A differential dynamic between the Omicron waves was found. The third wave was associated with lineage BA.1, characterized by a high number of cases, very fast displacement of Delta, doubling times of 3.3 days and a low level of lineage diversity and clustering. In contrast, the fourth wave was longer but associated with a lower number of cases, initially caused by BA.2, and later by BA.4/BA.5, with doubling times of about 10 days. Several BA.2 and BA.4/BA.5 sublineages and introductions were detected, although very few clusters with a constrained geographical distribution were observed, suggesting limited transmission chains. The differential dynamic could be due to waning immunity and an increase in population gatherings in the BA.1 wave, and a boosted population (for vaccination or recent prior immunity for BA.1 infection) in the wave caused by BA2/BA.4/BA.5, which may have limited the establishment of the new lineages.
dc.descriptionFil: Villanova, Gabriela Vanina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Laboratorio de Biotecnología Acuática. Centro Científico Tecnológico y Educativo Acuario del río Paraná; Argentina.
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.relationhttps://www.mdpi.com/1999-4915/15/2/312
dc.relationhttps://doi.org/10.3390/v15020312
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.rightsTorres, Carolina
dc.rightsNabaes Jodar, Mercedes
dc.rightsAcuña, Dolores
dc.rightsZambrana Montaño, Romina Micaela
dc.rightsCulasso, Andrés Carlos Alberto
dc.rightsAmadio, Ariel Fernando
dc.rightsAulicino, Paula
dc.rightsCeballos, Santiago
dc.rightsCacciabue, Marco
dc.rightsDebat, Humberto
dc.rightsDus Santos, María José
dc.rightsEberhardt, María Florencia
dc.rightsEspul, Carlos
dc.rightsFay, Fabián
dc.rightsFernández; María Ailén
dc.rightsFernández, Franco
dc.rightsFernandez Muñoz, Juan Manuel
dc.rightsFerrini, Florencia
dc.rightsGallego, Fernando
dc.rightsGiri, Adriana Angélica
dc.rightsCerri, Agustina
dc.rightsBolatti, Elisa María
dc.rightsGismondi, María Ines
dc.rightsGoya, Stephanie
dc.rightsGramundi, Iván
dc.rightsIrazoqui, José Matías
dc.rightsKönig, Guido Alberto
dc.rightsLeiva, Viviana
dc.rightsLucero, Horacio
dc.rightsMarquez, Nathalie
dc.rightsNardi, Cristina
dc.rightsOrtiz, Belén
dc.rightsPianciola, Luis
dc.rightsPintos, Carolina Beatriz
dc.rightsPuebla, Andrea Fabiana
dc.rightsRastellini, Carolina Victoria
dc.rightsRojas, Alejandro Ezequiel
dc.rightsSfalcin, Javier
dc.rightsSuárez, Ariel
dc.rightsTittarelli, Estefanía
dc.rightsToro, Rosana
dc.rightsVillanova, Gabriela Vanina
dc.rightsZiehm, María Cecilia
dc.rightsZimmermann, María Carla
dc.rightsZunino, Sebastián
dc.rightsProyecto PAIS Working Group
dc.rightsValinotto, Laura
dc.rightsViegas, Mariana
dc.rightsUniversidad Nacional de Rosario
dc.rightsAttribution 4.0 International (CC BY 4.0)
dc.rightsopenAccess
dc.subjectSARS-CoV-2
dc.subjectOmicron
dc.subjectSouth America
dc.subjectBA.1
dc.subjectBA.2
dc.subjectBA.4
dc.subjectBA.5
dc.titleOmicron waves in Argentina: dynamics of SARS-CoV-2 lineages BA.1, BA.2 and the emerging BA.2.12.1 and BA.4/BA.5
dc.typepublishedVersion
dc.typearticle
dc.typeartículo


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