Solid-state characterization of two polymorphic forms of R-albuterol sulfate

dc.creatorPalacios, M.A.
dc.creatorCuffini, S.
dc.creatorBadini, R.
dc.creatorKarlsson, A.
dc.creatorPalacios, S.M.
dc.date2007-03-12
dc.date.accessioned2023-08-30T17:09:23Z
dc.date.available2023-08-30T17:09:23Z
dc.identifierhttp://pa.bibdigital.ucc.edu.ar/4033/1/A_Palacios_Cuffini_Badini_Karlsson_Palacios.pdf
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8539762
dc.descriptionR-Albuterol (levalbuterol) is a drug used for asthma therapy and some formulations of it are in solid dosage forms. The aim of this work was to describe and characterize two polymorphic modifications of R-albuterol sulfate by means of typical structure-sensitive analytical techniques such as X-ray powder diffraction, FT-IR spectroscopy, visual and microscopic inspection, and DSC. Substantial differences were observed between the solid-state properties of the crystals, confirming the existence of at least two polymorphic forms for R-albuterol sulfate: Form I and Form II.
dc.descriptionFil: Palacios, M.A. Agencia Córdoba Ciencia SE, Unidad CEPROCOR, Santa Maria de Punilla 5164, Cordoba, Argentina
dc.descriptionFil: Cuffini, S. Agencia Córdoba Ciencia SE, Unidad CEPROCOR, Santa Maria de Punilla 5164, Cordoba, Argentina
dc.descriptionFil: Badini, R. Agencia Córdoba Ciencia SE, Unidad CEPROCOR, Santa Maria de Punilla 5164, Cordoba, Argentina
dc.descriptionFil: Karlsson, A. Facultad de Ciencias Exactas Físicas y Naturales, Universidad Nacional de Córdoba, 5000 Córdoba, Vélez Sarsfield 298, Argentina
dc.descriptionFil: Palacios, S.M. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina
dc.formatapplication/pdf
dc.languagespa
dc.publisherElseiver
dc.relationhttp://pa.bibdigital.ucc.edu.ar/4033/
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpba.2006.11.009
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.sourcePalacios, M.A., Cuffini, S., Badini, R., Karlsson, A. and Palacios, S.M. (2007) Solid-state characterization of two polymorphic forms of R-albuterol sulfate. Journal of Pharmaceutical and Biomedical Analysis, 43 (4). pp. 1531-1534. ISSN 0731-7085
dc.subjectR Medicina (General)
dc.titleSolid-state characterization of two polymorphic forms of R-albuterol sulfate
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/acceptedVersion


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