High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina

dc.creatorSola, C.
dc.creatorSaka, H.A.
dc.creatorVindel, A.
dc.creatorBocco, José Luis
dc.creatorMonterisi, A.
dc.creatorRocchi, M.
dc.creatorDíaz, E.
dc.creatorLomberghini, R.
dc.creatorLittvik, A.M.
dc.creatorLópez, T.
dc.creatorYudowsky, S.
dc.creatorCarvajal, L.
dc.creatorCulasso, C.
dc.creatorPerlo Morales, O.
dc.creatorAissa, M.S.
dc.creatorVilaro, M.
dc.creatorBongiovanni, M.E.
dc.creatorMangiaterra, S.
dc.creatorBarbon, S.
dc.creatorWolff, L.
dc.creatorVercelli, B.
dc.creatorD'Andrea, E.M.
dc.creatorLópez, A.
dc.creatorPino, Gustavo Ariel
dc.creatorMuñoz, V.
dc.creatorBottiglieri, Marina Teresita
dc.date2007-04-30
dc.date.accessioned2023-08-30T17:09:23Z
dc.date.available2023-08-30T17:09:23Z
dc.identifierhttp://pa.bibdigital.ucc.edu.ar/4030/1/A_Sola....pdf
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8539759
dc.descriptionIn the study presented here, the genetic characteristics of methicillin-susceptible Staphylococcus aureus (MSSA) strains isolated from patients attending hospitals in the city of Córdoba, Argentina, during 1999-2002 were evaluated to determine their genetic relationship with methicillin-resistant S. aureus (MRSA) clones as part of an effort to control the potential emergence of new epidemic MRSA strains. The results showed there is a high frequency of MSSA strains carrying Panton-Valentine leukocidin genes in invasive infections in Córdoba, Argentina, particularly in those occurring in hospital settings. Panton-Valentine leukocidin genes were found in the genomic background of one clone (ST30-N pulsotype) belonging to a successful internationally distributed MSSA lineage (clonal complex 30), which is closely related to the EMRSA-16 pandemic clone. These genes were also detected in the ancestral clone (ST5-M pulsotype) of the most prevalent MRSA epidemic clone causing healthcare-associated infections in this region, known as the Cordobes/Chilean clone. The molecular characterization of circulating MSSA strains, including the detection of Panton-Valentine leukocidin genes, is thus a useful marker for investigating the evolving epidemiology of hospital- and community-acquired MRSA clones.
dc.descriptionFil: Sola, C. Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Departamento de Bioquímica Clínica, Ciudad Universitaria, Córdoba 5000, Haya de la Torre y M. Allende s/n, Argentina
dc.descriptionFil: Saka, H.A. Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Departamento de Bioquímica Clínica, Ciudad Universitaria, Córdoba 5000, Haya de la Torre y M. Allende s/n, Argentina
dc.descriptionFil: Vindel, A. Laboratorio de Enfermedades Infecciosas Nosocomiales, Instituto de Salud Carlos III, Centro Nacional de Microbiología, Majadahonda, Madrid 28220, Spain
dc.descriptionFil: Bocco, José Luis. Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Departamento de Bioquímica Clínica, Ciudad Universitaria, Córdoba 5000, Haya de la Torre y M. Allende s/n, Argentina
dc.descriptionFil: Monterisi, A. Hospital Nacional de Clínicas, Argentina
dc.descriptionFil: Rocchi, M. Hospital Nacional de Clínicas, Argentina
dc.descriptionFil: Díaz, E. Hospital Militar de Córdoba
dc.descriptionFil: Lomberghini, R. Hospital Militar de Córdoba
dc.descriptionFil: Littvik, A.M. Hospital Rawson, Argentina
dc.descriptionFil: López, T. Hospital Rawson, Argentina
dc.descriptionFil: Yudowsky, S. Hospital Infantil
dc.descriptionFil: Carvajal, L. Hospital de Niños
dc.descriptionFil: Culasso, C. Hospital de Niños
dc.descriptionFil: Perlo Morales, O. Hospital Córdoba, Argentina
dc.descriptionFil: Aissa, M.S. Hospital Córdoba, Argentina
dc.descriptionFil: Vilaro, M. Hospital Privado de Córdoba, Argentina
dc.descriptionFil: Bongiovanni, M.E.Hospital Italiano de Córdoba, Argentina
dc.descriptionFil: Mangiaterra, S. Hospital Italiano de Córdoba, Argentina
dc.descriptionFil: Barbon, S. Hospital Italiano de Córdoba, Argentina
dc.descriptionFil: Wolff, L. Clinica Privada Velez Sarsfield, Argentina
dc.descriptionFil: Vercelli, B. Clinica Privada Velez Sarsfield, Argentina
dc.descriptionFil: D'Andrea, E.M. Hospital de Urgencias
dc.descriptionFil: López, A. Hospital de Urgencias
dc.descriptionFil: Pino, Gustavo Ariel. Hospital San Roque, Argentina
dc.descriptionFil: Muñoz, V. Hospital San Roque, Argentina
dc.descriptionFil: Bottiglieri, Marina Teresita. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
dc.formatapplication/pdf
dc.languagespa
dc.publisherSpringer Nature
dc.relationhttp://pa.bibdigital.ucc.edu.ar/4030/
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1007/s10096-007-0278-4
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.sourceSola, C., Saka, H.A., Vindel, A., Bocco, José Luis, Monterisi, A., Rocchi, M., Díaz, E., Lomberghini, R., Littvik, A.M., López, T., Yudowsky, S., Carvajal, L., Culasso, C., Perlo Morales, O., Aissa, M.S., Vilaro, M., Bongiovanni, M.E., Mangiaterra, S., Barbon, S., Wolff, L., Vercelli, B., D'Andrea, E.M., López, A., Pino, Gustavo Ariel, Muñoz, V. and Bottiglieri, Marina Teresita ORCID: https://orcid.org/0000-0001-6215-9488 <https://orcid.org/0000-0001-6215-9488> (2007) High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina. European Journal of Clinical Microbiology and Infectious Diseases, 26 (4). pp. 281-286. ISSN 0934-9723
dc.subjectR Medicina (General)
dc.titleHigh frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/acceptedVersion


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