Hepatitis C virus genotypes in Cordoba, Argentina. Unexpected high prevalence of genotype 2

dc.creatorRe, Viviana Elizabeth
dc.creatorLampe, Elisabeth
dc.creatorYoshida, Clara Fumiko
dc.creatorDe Oliveira, Jaqueline Mendes
dc.creatorLewis Ximenez, Lia
dc.creatorSpinsanti, Lorena
dc.creatorElbarcha, Osvaldo César
dc.creatorContigiani, Marta Silvia
dc.date2003-12-31
dc.date.accessioned2023-08-30T17:09:14Z
dc.date.available2023-08-30T17:09:14Z
dc.identifierhttp://pa.bibdigital.ucc.edu.ar/3965/1/A_Re_Lampe_Yoshida_DeOliveira_LewisXimenez_Spinsanti_Elbarcha_Contigiani.pdf
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8539694
dc.descriptionTo determine hepatitis C virus (HCV) genotypes circulating in the central region of Argentina, 96 consecutive anti-HCV positive subjects were studied. The presence of HCV RNA was detected in 60 samples by RT-nested PCR of the 5′ noncoding region (5′ NCR). Genotyping was performed by restriction fragment length polymorphism analysis of 5′ NCR region combined with PCR using type-specific primers of the core region. The groups of individuals in this study included hemophilia and hemodialysis patients, injecting drug users, screened blood donors, and patients with acute or chronic liver disease, all from Córdoba, Argentina. Overall, genotype 2 was the most prevalent (55.0%), followed by genotypes 1 (38.3%), and 3 (5.0%). Within genotype 1, subtype 1b was the most prevalent. An unexpected high prevalence of genotype 2 (61.9%) was found among patients with acute or chronic HCV infection (without known risk factors). These figures differ from other cohorts from East-Argentina where genotype 1 has been found as the most prevalent. This indicates that regional differences of genotype distribution might exist between Central and East Argentina.
dc.descriptionFil: Re, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina
dc.descriptionFil: Lampe, Elisabeth. Fundação Oswaldo Cruz, Departamento de Virologia, Laboratorio de Hepatities Virais, Rio de Janeiro, Brazil
dc.descriptionFil: Yoshida, Clara Fumiko. Fundação Oswaldo Cruz, Departamento de Virologia, Laboratorio de Hepatities Virais, Rio de Janeiro, Brazil
dc.descriptionFil: De Oliveira, Jaqueline Mendes. Fundação Oswaldo Cruz, Departamento de Virologia, Laboratorio de Hepatities Virais, Rio de Janeiro, Brazil
dc.descriptionFil: Lewis Ximenez, Lia. Fundação Oswaldo Cruz, Departamento de Virologia, Laboratorio de Hepatities Virais, Rio de Janeiro, Brazil
dc.descriptionFil: Spinsanti, Lorena Ivana. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina
dc.descriptionFil: Elbarcha, Osvaldo César. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina
dc.descriptionFil: Contigiani, Marta Silvia. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina
dc.formatapplication/pdf
dc.languagespa
dc.publisherInstituto de Investigaciones Medicas
dc.relationhttp://pa.bibdigital.ucc.edu.ar/3965/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.sourceRe, Viviana Elizabeth ORCID: https://orcid.org/0000-0002-4106-6642 <https://orcid.org/0000-0002-4106-6642>, Lampe, Elisabeth, Yoshida, Clara Fumiko, De Oliveira, Jaqueline Mendes, Lewis Ximenez, Lia, Spinsanti, Lorena ORCID: https://orcid.org/0000-0002-0157-4570 <https://orcid.org/0000-0002-0157-4570>, Elbarcha, Osvaldo César and Contigiani, Marta Silvia ORCID: https://orcid.org/0000-0002-7171-0013 <https://orcid.org/0000-0002-7171-0013> (2003) Hepatitis C virus genotypes in Cordoba, Argentina. Unexpected high prevalence of genotype 2. Medicina (Argentina), 63 (3). pp. 205-210. ISSN 0025-7680
dc.subjectQD Química
dc.titleHepatitis C virus genotypes in Cordoba, Argentina. Unexpected high prevalence of genotype 2
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/acceptedVersion


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