The spectrum of renal osteodystrophy in Argentina [Espectro bioquímico e histológico de la osteodistrofia renal en Argentina]

dc.creatorDouthat, Walter Guillermo
dc.creatorGaray, Gabriela
dc.creatorDe Arteaga, Javier
dc.creatorFernández Martín, J.L.
dc.creatorCannata Andía, J.B.
dc.creatorMassari, Pablo U.
dc.date2003-12-31
dc.date.accessioned2023-08-30T17:09:12Z
dc.date.available2023-08-30T17:09:12Z
dc.identifierhttp://pa.bibdigital.ucc.edu.ar/3953/1/A_Douthat_Garay_DeArteaga_Fern%C3%A1ndezMart%C3%ADn_CannataAnd%C3%ADa_Massari.pdf
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8539682
dc.descriptionBetween 1994-2001 we have performed 57 bone biopsies for diagnostic purposes in symptomatic CRF patients. We analyzed here 52 samples where the material was optimal for study, and divided them into 2 periods according to when the biopsy was performed: 1994-1996 and 1997-2001, to verify changes in the spectrum of renal osteodystrophy. Mean serum values were: serum calcium 9.9 ± 1.8 mg/dl, phosphate 5.8 ± 3.2 mg/dl, alkaline phosphatase 693.9 ± 968.9 UI/L, iPTH 562.0 ± 598.5 pg/ml, serum aluminum 65.7 ± 79.3 ug/L and bone aluminum 22.8 ± 22.4 ug/g. Hyperparathyroidism was the most common histological diagnosis as severe in 13 patients (25%), or as mild in 14 (27%). Ten patients had osteomalacia (19%), adynamic bone disease was diagnosed in 5 (9.6%) and mixed renal osteodystrophy in 10 (19.2%). Low bone turnover patients showed higher bone and serum aluminum than high bone turnover patients. We observed a relative increment in high turnover bone disease in the later period (1997-2001) without changes in low turnover bone disease. These data showed a high prevalence of hyperparathyroidism and aluminumrelated low turnover bone disease, with no significant changes between the two time-periods analyzed here.
dc.descriptionFil: Douthat, Walter Guillermo. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
dc.descriptionFil: Garay, Gabriela. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
dc.descriptionFil: De Arteaga, Javier. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
dc.descriptionFil: Fernández Martín, J.L. Universidad de Oviedo. Servicio de Metabolismo Óseo y Mineral, Instituto Reina Sodía de Investigación, Hospital Universitario Central de Asturias; España
dc.descriptionFil: Cannata Andía, J.B. Universidad de Oviedo. Servicio de Metabolismo Óseo y Mineral, Instituto Reina Sodía de Investigación, Hospital Universitario Central de Asturias; España
dc.descriptionFil: Massari, Pablo U. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
dc.formatapplication/pdf
dc.languagespa
dc.relationhttp://pa.bibdigital.ucc.edu.ar/3953/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.sourceDouthat, Walter Guillermo ORCID: https://orcid.org/0000-0002-4644-6003 <https://orcid.org/0000-0002-4644-6003>, Garay, Gabriela, De Arteaga, Javier, Fernández Martín, J.L., Cannata Andía, J.B. ORCID: https://orcid.org/0000-0001-6543-9960 <https://orcid.org/0000-0001-6543-9960> and Massari, Pablo U. (2003) The spectrum of renal osteodystrophy in Argentina [Espectro bioquímico e histológico de la osteodistrofia renal en Argentina]. Nefrologia, 23 (2). pp. 47-51. ISSN 0211-6995
dc.subjectR Medicina (General)
dc.titleThe spectrum of renal osteodystrophy in Argentina [Espectro bioquímico e histológico de la osteodistrofia renal en Argentina]
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/acceptedVersion


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