Natural Host Relationships and Genetic Diversity of Rodent-Associated Hantaviruses in Southeastern Brazil

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorMoro de Sousa, Ricardo Luiz
dc.creatorMoreli, Marcos Lazaro
dc.creatorBorges, Alessandra Abel
dc.creatorCampos, Gelse Mazzoni
dc.creatorLivonesi, Marcia Cristina
dc.creatorMoraes Figueiredo, Luiz Tadeu
dc.creatorPinto, Aramis Augusto
dc.date2014-05-20T13:16:03Z
dc.date2016-10-25T16:37:28Z
dc.date2014-05-20T13:16:03Z
dc.date2016-10-25T16:37:28Z
dc.date2008-01-01
dc.date.accessioned2017-04-05T19:33:19Z
dc.date.available2017-04-05T19:33:19Z
dc.identifierIntervirology. Basel: Karger, v. 51, n. 4, p. 299-310, 2008.
dc.identifier0300-5526
dc.identifierhttp://hdl.handle.net/11449/3017
dc.identifierhttp://acervodigital.unesp.br/handle/11449/3017
dc.identifier10.1159/000171818
dc.identifierWOS:000260892200014
dc.identifierhttp://dx.doi.org/10.1159/000171818
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/852783
dc.descriptionObjective: Hantaviruses are rodent-borne RNA viruses that have caused hantavirus cardiopulmonary syndrome in several Brazilian regions. In the present study, geographical distribution, seroprevalence, natural host range, and phylogenetic relations of rodent-associated hantaviruses collected from seven counties of Southeastern Brazil were evaluated. Methods: ELISA, RT-PCR and phylogenetic analysis were used in this study. Results: Antibodies to hantavirus were detected in Bolomys lasiurus, Akodon sp. and Oligoryzomys sp., performing an overall seroprevalence of 5.17%. All seropositive rodents were associated with grasslands or woods surrounded by sugar cane fields. Phylogenetic analysis of partial S- and M-segment sequences showed that viral sequences isolated from B. lasiurus specimens clustered with Araraquara virus. However, a sequence from Akodon sp. shared 100% similarity with Argentinian/Chilean viruses based on the partial S- segment amino acid sequence. Conclusion: These results indicate that there are associations between rodent reservoirs and hantaviruses in some regions of Southeastern Brazil, and suggest the existence of additional hantavirus genetic diversity and host ecology in these areas. Copyright (C) 2008 S. Karger AG, Basel
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageeng
dc.publisherKarger
dc.relationIntervirology
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectHantavirus
dc.subjectSigmodontine rodent
dc.subjectELISA
dc.subjectSeroprevalence
dc.subjectRT-PCR
dc.subjectSequencing phylogenetic reconstruction
dc.titleNatural Host Relationships and Genetic Diversity of Rodent-Associated Hantaviruses in Southeastern Brazil
dc.typeOtro


Este ítem pertenece a la siguiente institución