Prevalencia de defectos del tubo neural y estimación de casos evitados posfortificación en Argentina

Prevalence of neural tube defects and estimation of cases averted in the post-fortification period in Argentina

dc.creatorBidondo, María Paz
dc.creatorLiascovich, Rosa
dc.creatorBarbero, Pablo
dc.creatorGroisman, Boris
dc.date2021-02-09T21:56:38Z
dc.date2021-02-09T21:56:38Z
dc.date2015
dc.date.accessioned2023-08-29T20:09:22Z
dc.date.available2023-08-29T20:09:22Z
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/2306
dc.identifier10.5546/aap.2015.498
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8520649
dc.descriptionFil: Bidondo, María P. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS); Argentina.
dc.descriptionFil: Liascovich, Rosa. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS); Argentina.
dc.descriptionFil: Barbero, Pablo. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS); Argentina.
dc.descriptionFil: Groisman, Boris. Administración Nacional de Laboratorios e Institutos de Salud “Dr. Carlos G. Malbrán” (ANLIS); Argentina.
dc.descriptionPericonceptional intake of folic acid has demonstrated to be effective to reduce the frequency of neural tube defects, and food fortification has been one of the strategies implemented to increase it. An update is herein presented on the reduced prevalence of neural tube defect cases in the post-fortification period in Argentina and an estimation of cases averted in the 2005-2013 period as a result of this intervention. When comparing the prevalence observed in the post-fortification period to that reported in the pre-fortification period, anencephaly and encephalocele decreased by 66%, and spina bifida, by 47%, which were significant reductions. The estimated number of cases averted was higher for anencephaly, followed by spina bifida; encephalocele showed the lowest number of cases averted given that the prevalence of this defect was smaller. The decrease observed in the prevalence supports findings from previous studies on the impact of fortification.
dc.languagees
dc.relationArchivos argentinos de pediatria
dc.rightsopen
dc.subjectDefectos del Tubo Neural
dc.subjectDisrafia Espinal
dc.subjectAlimentos Fortificados
dc.subjectÁcido Fólico
dc.subjectPrevalencia
dc.titlePrevalencia de defectos del tubo neural y estimación de casos evitados posfortificación en Argentina
dc.titlePrevalence of neural tube defects and estimation of cases averted in the post-fortification period in Argentina
dc.typeArtículo


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