New transmission scenarios of the Argentine hemorrhagic fever since the introduction of the live attenuated junin virus vaccine (Candid #1): an experience in migrant workers

dc.creatorBriggiler, Ana M.
dc.creatorSinchi, Anabel
dc.creatorCoronel, Florencia
dc.creatorSánchez, Zaida
dc.creatorLevis, Silvana
dc.creatorTaylor, Jorge
dc.creatorEnria, Delia
dc.date2021-02-04T15:04:34Z
dc.date2021-02-04T15:04:34Z
dc.date2015
dc.date.accessioned2023-08-29T20:09:22Z
dc.date.available2023-08-29T20:09:22Z
dc.identifier1726-4634
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/2305
dc.identifierhttp://www.scielo.org.pe/scielo.php?pid=S1726-46342015000100023&script=sci_abstract
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8520647
dc.descriptionFil: Briggiler, Ana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
dc.descriptionFil: Sinchi, Anabel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
dc.descriptionFil: Coronel, Florencia. Ministerio de Salud de Santiago del Estero.Programa Ampliado de Inmunizaciones; Argentina.
dc.descriptionFil: Sánchez, Zaida. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
dc.descriptionFil: Levis, Silvana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
dc.descriptionFil: Taylor, Jorge. Registro Nacional de Trabajadores y Empleadores Agrarios; Argentina.
dc.descriptionFil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
dc.descriptionThe Argentine hemorrhagic fever (AHF) is a severe acute viral disease caused by the Junin virus of the Arenaviridae family. The AHF endemic area coincides geographically with the largest grain export agro-industrial complex of the country [Argentina]. Since the implementation of vaccination with the Candid #1 vaccine, a significant reduction in incidence was achieved and risk patterns were modified. A previous study allowed characterizing these changes and identifying three transmission scenarios: classic, emergent-reemergent, and traveler. The latter scenario includes seasonal migrant workers who move each year, mainly from the province of Santiago del Estero, the endemic area to work in the detasseling of maize. With the objective of protecting this group of workers, a prevention campaign was initiated which included: capacity building of health personnel in the province, health education, and immunization with the vaccine Candid #1. 3,021 workers were vaccinated. Prior to vaccination, serum samples were taken from a group of 104 volunteers. Tests for neutralizing antibodies specific to the Junin virus were performed and 6 (5.76%) tested positive. The unexpected finding of a high percentage of workers with antibodies suggests the need to evaluate several hypotheses: a) that the result is the product of non-probabilistic sampling; b) that it could be people who fell ill in previous travels, c) or who were vaccinated in previous travels; or d) consider this region as an emerging scenario.
dc.languagees
dc.relationRevista peruana de medicina experimental y salud pública
dc.rightsopen
dc.subjectFiebre Hemorrágica Americana
dc.subjectVirus Junin
dc.subjectVaccinia
dc.subjectArenavirus
dc.subjectSalud Pública
dc.titleLos nuevos escenarios de transmisión de la fiebre hemorrágica Argentina desde la introducción de la vacuna a virus junín vivo atenuado (Candid#1): una experiencia en trabajadores golondrinas
dc.titleNew transmission scenarios of the Argentine hemorrhagic fever since the introduction of the live attenuated junin virus vaccine (Candid #1): an experience in migrant workers
dc.typeArtículo


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