Utilidad del enzimoinmunoensayo en el diagnóstico de la tuberculosis
Usefulness of the enzyme immunoassay in the diagnosis of tuberculosis
| dc.creator | de Kantor, I N | |
| dc.creator | Barrera, Lucía | |
| dc.creator | Ritacco, Viviana | |
| dc.creator | Miceli, Isabel N. P. | |
| dc.date | 2020-12-21T20:53:48Z | |
| dc.date | 2020-12-21T20:53:48Z | |
| dc.date | 1991-06 | |
| dc.date.accessioned | 2023-08-29T20:08:04Z | |
| dc.date.available | 2023-08-29T20:08:04Z | |
| dc.identifier | 0030-0632 | |
| dc.identifier | http://sgc.anlis.gob.ar/handle/123456789/1961 | |
| dc.identifier | https://iris.paho.org/bitstream/handle/10665.2/16622/v110n6p461.pdf?sequence=1&isAllowed=y | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8519984 | |
| dc.description | Fil: de Kantor, I N. Centro Panamericano de Zoonosis (CEPANZO, OPS/OMS), Buenos Aires; Argentina. | |
| dc.description | Fil: Barrera, Lucía. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina. | |
| dc.description | Fil: Ritacco, Viviana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina. | |
| dc.description | Fil: Miceli, Isabel N. P. Dirección de Epidemiología, Ministerio de Salud, Buenos Aires; Argentina. | |
| dc.description | To assess the usefulness of enzyme immunoassay as a rapid method of diagnosing tuberculosis, a study was conducted of 687 serum samples from 271 children and 416 adults. With 55 sera from nontuberculous children as controls, the specificity was 0.98, and with 137 controls from the adult population, 0.93. Prior vaccination with BCG did not influence the level of detectable anti-PPD antibody. The results were similar in healthy PPD-positive and negative adults. The test differentiated mycoses and nontuberculous mycobacterioses from tuberculosis. The sensitivity rates in 49 children and 200 adults diagnosed with bacteriologically confirmed pulmonary and extrapulmonary tuberculosis were calculated at 0.51 and 0.69, respectively. In those tuberculosis cases not bacteriologically confirmed or at other sites, the test was positive in 28.1% of 114 children and in 48.6% of 35 adults. The cost, speed, and availability of reagents for this test were comparable to those for direct microscopic examination. Both methods were positive for 49% of the tuberculosis cases confirmed by culture, and a total of 84% of those cases were found positive using one method or the other. It is concluded that enzyme immunoassay can be especially useful in the rapid diagnosis of nonbacilliferous pulmonary, extrapulmonary, and childhood tuberculosis. | |
| dc.format | ||
| dc.language | es | |
| dc.relation | Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau | |
| dc.rights | open | |
| dc.source | Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau 1991 Jun;110(6):461-70. | |
| dc.subject | Técnicas para Inmunoenzimas | |
| dc.subject | Tuberculosis | |
| dc.title | Utilidad del enzimoinmunoensayo en el diagnóstico de la tuberculosis | |
| dc.title | Usefulness of the enzyme immunoassay in the diagnosis of tuberculosis | |
| dc.type | Artículo |