Fatal canine encephalitozoonosis in Latin America, first report

dc.creatorPostma, Gabriela Cintia
dc.creatorPardini, Lais
dc.creatorCarnevale, Silvana
dc.creatorGregnoli, Elena
dc.creatorQuiroga, María Alejandra
dc.creatorVenturini, María Cecilia
dc.creatorMinatel, Leonardo
dc.date2020-12-16T10:09:50Z
dc.date2020-12-16T10:09:50Z
dc.date2018-01
dc.date.accessioned2023-08-29T20:07:53Z
dc.date.available2023-08-29T20:07:53Z
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1917
dc.identifier10.1016/j.vprsr.2017.11.007
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519897
dc.descriptionFil: Postma, Gabriela Cintia. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina.
dc.descriptionFil: Pardini, Lais. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Laboratorio de Inmunoparasitología; Argentina.
dc.descriptionFil: Carnevale, Silvana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Parasitología; Argentina.
dc.descriptionFil: Gregnoli, Elena. Actividad privada; Argentina.
dc.descriptionFil: Quiroga, María Alejandra. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Laboratorio de Patología Especial Veterinaria; Argentina.
dc.descriptionFil: Venturini, María Cecilia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Laboratorio de Inmunoparasitología; Argentina.
dc.descriptionFil: Minatel, Leonardo. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina.
dc.descriptionEncephalitozoon cuniculi is an obligate, intracellular microsporidian organism capable of establish infection in a wide variety of animals. In carnivores it may cause a sporadic, severe disease in the first few months of life, which usually culminates with the death of the animal. The objective of this study was to report a natural fatal case of encephalitozoonosis in a puppy from Argentina. Clinical signs included reduced appetite, depression, vocalizing, weight loss, weakness, convulsions and recumbency. No significant gross lesions were noticed at necropsy. Microscopically, severe, diffuse, lymphocytic encephalitis was seen. Large cytoplasmic vacuoles containing spores, morphologically compatible with E. cuniculi, were present within endothelial cells of brain and kidney, in renal tubular epithelium and hepatocytes. Encephalitozoon cuniculi DNA was detected by PCR in the kidney. Antibody titers to E. cuniculi in serum from the surviving puppies and the dam were ≥1:200. This report contributes to our understanding of neurologic disease in puppies. Encephalitozoonosis should be considered as a differential diagnosis in cases of fatal encephalitis in puppies.
dc.languageen
dc.publisherElsevier
dc.relation#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.relationdatasets
dc.relationVeterinary parasitology, regional studies and reports
dc.rightsnone
dc.sourceVeterinary Parasitology: Regional Studies and Reports 2018; 11:15-18
dc.subjectEncefalitis
dc.subjectEncephalitozoon cuniculi
dc.subjectNefritis
dc.subjectFactores de Edad
dc.subjectAnimales
dc.subjectAnticuerpos Antifúngicos
dc.subjectEncéfalo
dc.subjectDiagnóstico Diferencial
dc.subjectEnfermedades de los Perros
dc.subjectPerros
dc.subjectEncefalitozoonosis
dc.subjectResultado Fatal
dc.subjectFemenino
dc.subjectRiñón
dc.subjectAmérica Latina
dc.titleFatal canine encephalitozoonosis in Latin America, first report
dc.typeArtículo


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