Transmision nosocomial de Candida albicans en recién nacidos

Nosocomial transmission of Candida albicans in newborn infants

dc.creatorRodero, Laura
dc.creatorHochenfellner, F.
dc.creatorDemkura, H
dc.creatorPereda, G
dc.creatorCórdoba, Susana
dc.creatorCanteros, Cristina
dc.creatorRial, Marcela Silvina
dc.creatorDavel, Graciela
dc.date2020-12-14T19:38:12Z
dc.date2020-12-14T19:38:12Z
dc.date2000
dc.date.accessioned2023-08-29T20:07:47Z
dc.date.available2023-08-29T20:07:47Z
dc.identifier0325-7541
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1884
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519830
dc.descriptionFil: Rodero, Laura. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina.
dc.descriptionFil: Hochenfellner, F. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina.
dc.descriptionFil: Demkura, H. Laboratorio Microbiología Hospital De Niños Superiora Sor María Ludovica; Argentina.
dc.descriptionFil: Pereda, G. Laboratorio Microbiología Hospital De Niños Pedro Elizalde; Argentina.
dc.descriptionFil: Córdoba, Susana. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina.
dc.descriptionFil: Canteros, Cristina. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina.
dc.descriptionFil: Rial, Marcela Silvina. Laboratorio Microbiología Hospital De Niños Pedro Elizalde; Argentina.
dc.descriptionFil: Davel, Graciela. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina.
dc.descriptionCandida spp. colonization in neonates occurs due to vertical or horizontal transmission. Preliminary studies determined that Candida albicans is the principal agent of these infections. In order to establish nosocomial transmission, 26 Candida albicans strains isolated from patients with candidosis hospitalized during a 18-month period in 2 neonatal intensive care units (NICU) from a pediatric hospital were studied. Fourteen isolates from patients and health care workers, involved in possible outbreaks of an intensive care unit (UCI) and a NICU from another pediatric hospital were also studied. All Candida albicans strains were genotyped by Southern blot hybridization with 27A. Isolates for outbreak confirmation were also hybridized with another specific Candida albicans probe, Ca3. Hybridization patterns demonstrated horizontal transmission in all the units studied. In a NICU, transmission among 4 patients during a 10-month period could be established and in the other NICU, 3 cases of transmission among 2 patients each were demonstrated in periods of 2 to 20 days. The outbreak studies showed the same strain isolated from 2 nurses and from one patient at the NICU and at the ICU identical strains were found in 3 patients. In this study, hybridization with Ca3 in addition to 27A probe did not increase discrimination power among isolates. Genotypic analysis allows, not only, determination of transmission and persistence of strains during prolonged periods or in sporadic outbreaks, but also facilitates necessary epidemiological decisions for optimizing nosocomial fungal infection control measures.
dc.languagees
dc.relationRevista Argentina de microbiologia
dc.rightsopen
dc.sourceRevista Argentina de Microbiología 2000; 32(4):179-84.
dc.subjectCandida albicans
dc.subjectMicosis
dc.titleTransmision nosocomial de Candida albicans en recién nacidos
dc.titleNosocomial transmission of Candida albicans in newborn infants
dc.typeArtículo


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