Epidemiology of snakebite and use of antivenom in Argentina

dc.creatorDolab, Jorge A.
dc.creatorde Roodt, Adolfo R.
dc.creatorde Titto, Ernesto Horacio
dc.creatorGarcía, Susana Isabel
dc.creatorFunes, Raúl F
dc.creatorSalomón, Oscar Daniel
dc.creatorChippaux, Jean-Philippe
dc.date2020-12-10T14:29:08Z
dc.date2020-12-10T14:29:08Z
dc.date2014-05
dc.date.accessioned2023-08-29T20:07:41Z
dc.date.available2023-08-29T20:07:41Z
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1866
dc.identifier10.1093/trstmh/tru038
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519790
dc.descriptionFil: Dolab, Jorge Adrián. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Producción de Biológicos; Argentina.
dc.descriptionFil: de Roodt, Adolfo Rafael. Universidad de Buenos Aires. Facultad de Medicina. Centro de Patología Experimental y Aplicada. Laboratorio de Toxinopatología; Argentina.
dc.descriptionFil: de Titto, Ernesto Horacio. Ministerio de Salud. Dirección Nacional de Determinantes de la Salud e Investigación; Argentina.
dc.descriptionFil: García, Susana Isabel. Ministerio de Salud. Dirección Nacional de Determinantes de la Salud e Investigación; Argentina.
dc.descriptionFil: Funes, Raúl. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Producción de Biológicos; Argentina.
dc.descriptionFil: Salomón, Oscar Danie. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Medicina Tropical; Argentina.
dc.descriptionFil: Chippaux, Jean-Philippe. Institut de Recherche pour le Développement; Francia.
dc.descriptionBackground: The incidence and case fatality rate of snakebite in Argentina are poorly known. Methods: The authors used questionnaires provided with antivenoms by the primary manufacturer of anti-venoms in Argentina. Results: A total of 8083 completed questionnaires was collected between 1978 and 1998. The annual incidence of snakebite was 1.8 bites per 100,000 inhabitants, with a high geographical heterogeneity; in the northern provinces of the country, the incidence can exceed 150 snakebites per 100,000 people per year. Bothrops (pit viper) bites predominated, accounting for 96.6% (6720/6957) of envenomations, bites from Crotalus (rattlesnake) accounted for 2.8% (195/6957), and bites from Micrurus (coral snake) for 0.6% (42/6957). Most patients were young men, who were generally bitten during agricultural activities, i.e. while working in the fields. Most snakebites (78.9%, 5852/7419) were to the lower limb, including 58.3% (4322/7419) to the foot. The case fatality rate was <0.04% (3/8083). Most envenomations (90%, 7275/8083) were treated with specific antivenom during the first 4 h after the bite. The median dose of antivenom was two vials for viper bites (Bothrops and Crotalus) and three vials for Micrurus bites. Conclusion: These preliminary results should enable manufacturers to increase the availability of appropriate antivenom and health authorities to improve the management of snakebites where they are most common.
dc.languageen
dc.publisherOxford University Press
dc.relation#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.relationdatasets
dc.relationTransactions of the Royal Society of Tropical Medicine and Hygiene
dc.rightsnone
dc.sourceTransactions of The Royal Society of Tropical Medicine and Hygiene 2014 ; 108(5):269-276
dc.subjectArgentina
dc.subjectBothrops
dc.subjectCrotalus
dc.subjectSerpientes de Coral
dc.subjectMordeduras de Serpientes
dc.subjectAnimales
dc.subjectAntivenenos
dc.subjectEsquema de Medicación
dc.subjectServicio de Urgencia en Hospital
dc.subjectFemenino
dc.subjectHumanos
dc.subjectMasculino
dc.subjectEstaciones del Año
dc.subjectEncuestas y Cuestionarios
dc.subjectResultado del Tratamiento
dc.subjectElapidae
dc.titleEpidemiology of snakebite and use of antivenom in Argentina
dc.typeArtículo


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