Distribution of PCV13 and PPSV23 Streptococcus pneumoniae serotypes in Argentinean adults with invasive disease, 2013-2017

dc.creatorZintgraff, Jonathan
dc.creatorFossati, M. S.
dc.creatorSorhouet Pereira, Cecilia
dc.creatorVeliz, Omar
dc.creatorRegueira, Mabel
dc.creatorMoscoloni, Maria Alicia
dc.creatorIrazu, Lucía
dc.creatorLara, Claudia
dc.creatorNapoli, Daniela
dc.date2020-12-04T09:11:03Z
dc.date2020-12-04T09:11:03Z
dc.date2020
dc.date.accessioned2023-08-29T20:07:33Z
dc.date.available2023-08-29T20:07:33Z
dc.identifier0325-7541
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1824
dc.identifier10.1016/j.ram.2019.11.004
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519716
dc.descriptionFil: Zintgraff, Jonathan. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Fossati, M. S. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Sorhouet Pereira, Cecilia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Veliz, Omar. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Regueira, Mabel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Moscoloni, Maria Alicia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Irazu, Lucía. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Lara, Claudia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionFil: Napoli, Daniela. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Bacteriología. Servicio de Bacteriología Clínica; Argentina.
dc.descriptionStreptococcus pneumoniae is a major cause of severe invasive disease associated with high mortality and morbidity worldwide. To identify the serotypes most commonly associated with infection in adults in Argentina, 791 pneumococcal isolates from 56 hospitals belonging to 16 provinces and Buenos Aires city were serotyped. The isolates were submitted as part of a National Surveillance Program for invasive pneumococcal disease in adults, which started in 2013. Serotypes 3, 8, 12F, 7F and 1 were the most prevalent among adult patients. During the study period there was no significant difference in serotype distribution between the age groups studied (18-64 and ≥65 years old), except for serotype 1, 3 and 23A. Most prevalent serotypes in pneumonia were serotype 7F, 1, 12F, 8, and 3. When the clinical diagnosis was meningitis, serotype 3 and 12F were the most prevalent, whereas when the diagnosis was sepsis/bacteremia the most prevalent was serotype 8. In this work, for the 18-64-year-old group, PPSV23 and PCV13 serotypes accounted for 74.56% and 44.54% respectively of the cases in the studied period. On the other hand, for the ≥65-year-old group, these serotypes represented 72.30% and 41.42% respectively. The aim of this work was to establish the knowledge bases of the serotypes that cause invasive pneumococcal diseases in the adult population in Argentina and to be able to detect changes in their distribution over time in order to explore the potential serotype coverage of the vaccines in current use.
dc.formatpdf
dc.languageen
dc.relationRevista Argentina de microbiologia
dc.rightsopen
dc.sourceRevista Argentina de microbiologia 2020;52(3):189-194.
dc.subjectVacunas
dc.subjectNeumonía Neumocócica
dc.subjectEpidemiología
dc.subjectStreptococcus pneumoniae
dc.titleDistribution of PCV13 and PPSV23 Streptococcus pneumoniae serotypes in Argentinean adults with invasive disease, 2013-2017
dc.typeArtículo


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