Diversity of picornaviruses in rural Bolivia

dc.creatorNix, W Allan
dc.creatorKhetsuriani, Nino
dc.creatorPeñaranda, Silvia
dc.creatorMaher, Kaija
dc.creatorVenczel, Linda
dc.creatorCselkó, Zsuzsa
dc.creatorFreire, María Cecilia
dc.creatorCisterna, Daniel
dc.creatorLema, Cristina L.
dc.creatorRosales, Patricia
dc.creatorRodriguez, Jacqueline R
dc.creatorRodriguez, Wilma
dc.creatorHalkyer, Percy
dc.creatorRonveaux, Olivier
dc.creatorPallansch, Mark A.
dc.creatorOberste, M. Steven
dc.date2020-11-24T12:55:06Z
dc.date2020-11-24T12:55:06Z
dc.date2013-09
dc.date.accessioned2023-08-29T20:07:10Z
dc.date.available2023-08-29T20:07:10Z
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1714
dc.identifier10.1099/vir.0.053827-0
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519526
dc.descriptionFil: Nix, W Allan. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionFil: Khetsuriani, Nino. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionFil: Peñaranda, Silvia. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionFil: Maher, Kaija. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionFil: Venczel, Linda. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionFil: Cselkó, Zsuzsa. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionFil: Freire, Maria Cecilia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
dc.descriptionFil: Cisterna, Daniel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
dc.descriptionFil: Lema, Cristina L. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
dc.descriptionFil: Rosales, Patricia. Ministry of Health and Sports; Bolivia.
dc.descriptionFil: Rodríguez, Jacqueline R. Pediatric Hospital San Antonio de Los Sauces; Bolivia.
dc.descriptionFil: Rodríguez, Wilma. Ministry of Health and Sports; Bolivia.
dc.descriptionFil: Halkyer, Percy. Pan-American Health Organization; Bolivia.
dc.descriptionFil: Ronveaux, Olivier. Pan-American Health Organization; Bolivia.
dc.descriptionFil: Pallansch, Mark A. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionFil: Oberste, M Steven. Centers for Disease Control and Prevention; Estados Unidos.
dc.descriptionThe family Picornaviridae is a large and diverse group of viruses that infect humans and animals. Picornaviruses are among the most common infections of humans and cause a wide spectrum of acute human disease. This study began as an investigation of acute flaccid paralysis (AFP) in a small area of eastern Bolivia, where surveillance had identified a persistently high AFP rate in children. Stools were collected and diagnostic studies ruled out poliovirus. We tested stool specimens from 51 AFP cases and 34 healthy household or community contacts collected during 2002-2003 using real-time and semi-nested reverse transcription polymerase chain reaction assays for enterovirus, parechovirus, cardiovirus, kobuvirus, salivirus and cosavirus. Anecdotal reports suggested a temporal association with neurological disease in domestic pigs, so six porcine stools were also collected and tested with the same set of assays, with the addition of an assay for porcine teschovirus. A total of 126 picornaviruses were detected in 73 of 85 human individuals, consisting of 53 different picornavirus types encompassing five genera (all except Kobuvirus). All six porcine stools contained porcine and/or human picornaviruses. No single virus, or combination of viruses, specifically correlated with AFP; however, the study revealed a surprising complexity of enteric picornaviruses in a single community.
dc.formatpdf
dc.languageen
dc.publisherMicrobiology Society
dc.relation#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.relationdatasets
dc.relationThe Journal of general virology
dc.rightsopen
dc.sourceJournal of General Virology 2013; 94(0 9): 2017–2028
dc.subjectAdolescente
dc.subjectAnimales
dc.subjectBolivia
dc.subjectNiño
dc.subjectPreescolar
dc.subjectHeces
dc.subjectHumanos
dc.subjectLactante
dc.subjectEpidemiología Molecular
dc.subjectDatos de Secuencia Molecular
dc.subjectParaplejía
dc.subjectPicornaviridae
dc.subjectInfecciones por Picornaviridae
dc.subjectReacción en Cadena en Tiempo Real de la Polimerasa
dc.subjectReacción en Cadena de la Polimerasa de Transcriptasa Inversa
dc.subjectPoblación Rural
dc.subjectAnálisis de Secuencia de ADN
dc.subjectPorcinos
dc.subjectEnfermedades de los Porcinos
dc.subjectAdulto Joven
dc.titleDiversity of picornaviruses in rural Bolivia
dc.typeArtículo


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