dc.creatorRiarte, Adelina
dc.creatorLuna, María Concepción
dc.creatorSabatiello, R
dc.creatorSinagra, Angel
dc.creatorSchiavelli, R.
dc.creatorDe Rissio, Ana María
dc.creatorMaiolo, E. I.
dc.creatorGarcía, Miriam Martin
dc.creatorJacob, Néstor R.
dc.creatorPattin, M
dc.creatorLauricella, Marta A.
dc.creatorSegura, Elsa L.
dc.creatorVázquez, Miryam
dc.date2019-12-12T20:13:59Z
dc.date2019-12-12T20:13:59Z
dc.date1999-09
dc.date.accessioned2023-08-29T20:06:40Z
dc.date.available2023-08-29T20:06:40Z
dc.identifier1058-4838
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1499
dc.identifier10.1086/598634
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519237
dc.descriptionChagas' disease was present in 17.22% of persons undergoing kidney transplantation in an Argentine Hospital. The criterion for attributing reactivation of chronic Chagas' disease and transmission of Trypanosoma cruzi to grafts was detection of parasites in blood (patent parasitemia) or tissues. Reactivation was diagnosed in 5 (21.7%) of 23 recipients. Ten (43.4%) of 23 chagasic recipients without reactivation of chronic Chagas' disease had abrogation of serological reactivity. T. cruzi infection was transmitted to 3 (18.7%) of 16 non-chagasic recipients. Reactivation and infection were diagnosed by patent parasitemia or cutaneous panniculitis. For diagnosis, detection of parasites in blood and tissues had more relevance than serology. Sequential monitoring detected early reactivation and infection, permitting application of preemptive or therapeutic therapy with benznidazole, thus inhibiting, in all patients, severe clinical disease produced by a progressive and systemic replication of the parasite.
dc.languageen
dc.relationClinical infectious diseases : an official publication of the Infectious Diseases Society of America
dc.rightsnone
dc.titleChagas' disease in patients with kidney transplants: 7 years of experience 1989-1996
dc.typeArtículo


Este ítem pertenece a la siguiente institución