Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study

dc.creatorCaini, Saverio
dc.creatorHuang, Q Sue
dc.creatorCiblak, Meral A
dc.creatorKusznierz, Gabriela F.
dc.creatorOwen, Rhonda
dc.creatorWangchuk, Sonam
dc.creatorHenriques, Cláudio M P
dc.creatorNjouom, Richard
dc.creatorFasce, Rodrigo A
dc.creatorYu, Hongjie
dc.creatorFeng, Luzhao
dc.creatorZambon, Maria
dc.creatorClara, Alexey W
dc.creatorKosasih, Herman
dc.creatorPuzelli, Simona
dc.creatorKadjo, Hervé A
dc.creatorEmukule, Gideon O
dc.creatorHeraud, Jean-Michel
dc.creatorAng, Li Wei
dc.creatorVenter, Marietjie
dc.creatorMironenko, Alla
dc.creatorBrammer, Lynnette
dc.creatorMai, Le Thi Quynh
dc.creatorSchellevis, François
dc.creatorPlotkin, Stanley
dc.creatorPaget, John
dc.date2019-11-27T19:11:33Z
dc.date2019-11-27T19:11:33Z
dc.date2015-08
dc.date.accessioned2023-08-29T20:06:16Z
dc.date.available2023-08-29T20:06:16Z
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1385
dc.identifier10.1111/irv.12319
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519051
dc.descriptionINTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS: Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type. RESULTS: The database included 935 673 influenza cases (2000-2013). Overall median proportion of influenza B was 22·6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5-17 years) than patients infected with influenza A. CONCLUSION: Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza.
dc.languageen
dc.relationInfluenza and other respiratory viruses
dc.rightsopen
dc.subjectEstudio Global de Influenza B (GIBS)
dc.subjectCarga de enfermedad
dc.subjectEpidemiología
dc.subjectGripe Humana
dc.subjectVacunación
dc.subjectvaccine mismatch
dc.titleEpidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
dc.typeArtículo


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