Faecal IgA concentration is influenced by age in dogs

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorZaine, Leandro
dc.creatorFerreira, Chayanne
dc.creatorGomes, Marcia de O. S.
dc.creatorMonti, Mariana
dc.creatorTortola, Leticia
dc.creatorVasconcellos, Ricardo S.
dc.creatorCarciofi, Aulus C.
dc.date2014-05-20T13:14:20Z
dc.date2014-05-20T13:14:20Z
dc.date2011-10-01
dc.date.accessioned2017-04-05T19:26:06Z
dc.date.available2017-04-05T19:26:06Z
dc.identifierBritish Journal of Nutrition. Cambridge: Cambridge Univ Press, v. 106, p. S183-S186, 2011.
dc.identifier0007-1145
dc.identifierhttp://hdl.handle.net/11449/1843
dc.identifier10.1017/S0007114511000559
dc.identifierWOS:000296609400039
dc.identifierWOS000296609400039.pdf
dc.identifierhttp://dx.doi.org/10.1017/S0007114511000559
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/851842
dc.descriptionData comparing age-related alterations in faecal IgA concentrations of dogs are not available in the literature. The present study aimed to compare the faecal concentrations of IgA in puppies, mature and senior dogs. A total of twenty-four beagle dogs were used, including eight puppies (5 months old, four females and four males), eight mature (4.6 years old, eight males) and eight senior dogs (10.6 years old, three males and five females). Fresh faecal samples were collected from each dog for three consecutive days and pooled by animal. After saline extraction, IgA content was measured by ELISA. Data were analysed by one-way ANOVA, and means were compared with Tukey's test (P<0.05). Results showed that puppies have lower faecal IgA concentrations than mature dogs (P<0.05); senior animals presented intermediary results. The reduced faecal IgA concentration in puppies is consistent with the reduced serum and salivary IgA concentrations reported previously, suggesting a reduced mucosal immunity in this age group. Although some studies have found an increased serum IgA concentration in older dogs, this may differ from the intestinal secretion of IgA, which appears to be lower in some senior animals (four of the eight dogs studied).
dc.languageeng
dc.publisherCambridge University Press
dc.relationBritish Journal of Nutrition
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectageing
dc.subjectImmunology
dc.subjectMucosal immunity
dc.subjectPuppies
dc.titleFaecal IgA concentration is influenced by age in dogs
dc.typeOtro


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