Application of variable number of tandem repeats typing to describe familial outbreaks of brucellosis in Argentina

dc.creatorLucero, Nidia E.
dc.creatorTenenbaum, Marina
dc.creatorJacob, Néstor R.
dc.creatorEscobar, Gabriela I.
dc.creatorGroussaud, Pauline
dc.creatorWhatmore, Adrian M.
dc.date2012-11-15T11:31:10Z
dc.date2012-11-15T11:31:10Z
dc.date2010
dc.date.accessioned2023-08-29T20:03:44Z
dc.date.available2023-08-29T20:03:44Z
dc.identifier0022-2615
dc.identifierhttps://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.017525-0
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/361
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8517658
dc.descriptionFil: Lucero, Nidia E. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Laboratorio de Brucelosis; Argentina.
dc.descriptionFil: Jacob, Néstor R. Hospital Dr. Cosme Argerich. Departamento de Infectologia; Argentina.
dc.descriptionFil: Tenenbaum, Marina. Hospital de Pediatria Dr. Ricardo Gutierrez. Departamento de Infectologia; Argentina.
dc.descriptionFil: Escobar, Gabriela I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Laboratorio de Brucelosis; Argentina.
dc.descriptionFil: Groussaud, Pauline. Veterinary Laboratories Agency. Department of Statutory and Exotic Bacterial Diseases. Brucellosis Reference Unit; Reino Unido.
dc.descriptionFil: Whatmore, Adrian M. Veterinary Laboratories Agency. Department of Statutory and Exotic Bacterial Diseases. Brucellosis Reference Unit; Reino Unido.
dc.descriptionConsumption of inadequately pasteurized dairy products is the most common means of transmission of brucellosis. This report describes two foodborne outbreaks that occurred in families infected after consumption of fresh home-made cheese bought in different Argentine provinces. High resolution variable number of tandem repeats (VNTR)-based analysis revealed two well-defined groups comprising essentially identical profiles and corresponding to the two different outbreaks. Similar clinical findings in members of the same family could indicate that the differential virulence of different bacterial clones, as indicated by VNTR data, could have influenced the course of the disease. We observed the importance of adequate treatment in early stages of the disease; combination therapy and extended treatment for 6 weeks or longer yielded significantly better results. The risk of the foodborne transmission of this zoonotic disease and disease prevention should be considered.
dc.formatapplication/pdf
dc.languageen
dc.relationJournal of medical microbiology
dc.rightsnone
dc.sourceJournal of Medical Microbiology, 2010, 59(6), 648–652.
dc.subjectBrucelosis
dc.subjectSecuencias Repetidas en Tandem
dc.subjectArgentina
dc.subjectEnfermedades Transmitidas por los Alimentos
dc.titleApplication of variable number of tandem repeats typing to describe familial outbreaks of brucellosis in Argentina
dc.typeArtículo
dc.coverageARG


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