dc.creatorSanabria Quiroga, Álvaro Enrique
dc.creatorVillegas Lanau, María Isabel
dc.creatorMorales Uribe, Carlos Hernando
dc.date2022-03-01T16:32:05Z
dc.date2022-03-01T16:32:05Z
dc.date2005
dc.date.accessioned2023-08-28T20:43:12Z
dc.date.available2023-08-28T20:43:12Z
dc.identifierSanabria AE, Morales CH, Villegas MI. Laparoscopic repair for perforated peptic ulcer disease. Cochrane Database Syst Rev. 2005 Oct 19;(4):CD004778. doi: 10.1002/14651858.CD004778.pub2. Update in: Cochrane Database Syst Rev. 2013;28(2):CD004778. PMID: 16235381.
dc.identifier1361-6137
dc.identifierhttp://hdl.handle.net/10495/26345
dc.identifier10.1002/14651858.CD004778
dc.identifier1469-493X
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8483304
dc.descriptionABSTRACT: BackgroundPerforated peptic ulcer is a common abdominal disease that is treated by surgery. The development of laparoscopic surgery has changedthe way to treat such abdominal surgical emergencies. The results of some clinicaltrials suggestthatlaparoscopic surgery could be a betterstrategy than open surgery in the correction of perforated peptic ulcer butthe evidence is not strongly in favour or againstthis intervention.ObjectivesTo measure the eHect of laparoscopic surgical treatment versus open surgical treatment in patients with a diagnosis of perforated pepticulcer in relation to abdominal septic complications, surgical wound infection, extra-abdominal complications, hospital length of stay anddirect costs.Search methodsWe searched the Cochrane Central Register of Controlled Trials (CENTRAL) on The Cochrane Library (Issue 2, 2004), PubMed/MEDLINE (1966to July 2004), EMBASE (1985 toNovember 2004) and LILACS (1988 toNovember 2004) as well as reference lists ofrelevant articles. Searchesin all databases were updated in December 2009. We did not confine our search to English language publications.Selection criteriaRandomized clinical trials comparing laparoscopic surgery versus open surgery for the repair of perforated peptic ulcer using anymechanical method of closure (suture, omental patch or fibrin sealant).Data collection and analysisPrimary outcome measures included proportion of septic and other abdominal complications (surgical site infection, suture leakage, intraabdominal abscess, postoperative ileus) and extra-abdominal complications (pulmonary). Secondary outcomes included mortality, timeto return to normal diet, time of nasogastric aspiration, hospital length-of-stay and costs. Outcomes were summarized by reporting oddsratios and 95% confidence intervals, using the fixed-eHect model.Main resultsWe included three randomised clinical trials of acceptable quality. We found no statistically significant diHerences between laparoscopicand open surgery in the proportion of abdominal septic complications (OR 0.66, 95% CI 0.30 to 1.47), pulmonary complications (OR 0.52;95% CI 0.08 to 3.55) or number of septic abdominal complications (0.60, 95% CI 0.32 to 1.15). Heterogeneity was significant for pulmonarycomplications and operating time  
dc.descriptionCOL0007121
dc.descriptionCOL0016612
dc.format23
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherWiley
dc.publisherGrupo Académico de Epidemiología Clínica
dc.publisherTrauma y Cirugía
dc.publisherOxford, Reino Unido
dc.relationCochrane Database Syst Rev
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectHumanos
dc.subjectHumans
dc.subjectLaparoscopía
dc.subjectLaparoscopy
dc.subjectÚlcera Péptica Perforada - cirugía
dc.subjectPeptic Ulcer Perforation - surgery
dc.titleLaparoscopic repair for perforated peptic ulcer disease (Review)
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_dcae04bc
dc.typehttps://purl.org/redcol/resource_type/ARTREV
dc.typeArtículo de revisión


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