| dc.creator | Sánchez Caraballo, Jorge Mario | |
| dc.creator | Cardona Villa, Ricardo | |
| dc.creator | Álvarez Ricardo, Leidy Lucía | |
| dc.date | 2023-01-19T17:37:13Z | |
| dc.date | 2023-01-19T17:37:13Z | |
| dc.date | 2022 | |
| dc.date.accessioned | 2023-08-28T20:33:37Z | |
| dc.date.available | 2023-08-28T20:33:37Z | |
| dc.identifier | Sánchez J, Álvarez L, Cardona R. Prospective analysis of clinical evolution in chronic urticaria: Persistence, remission, recurrence, and pruritus alone. World Allergy Organ J. 2022 Oct 8;15(10):100705. doi: 10.1016/j.waojou.2022.100705. | |
| dc.identifier | https://hdl.handle.net/10495/33179 | |
| dc.identifier | 10.1016/j.waojou.2022.100705 | |
| dc.identifier | 1939-4551 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8481037 | |
| dc.description | ABSTRACT: Background: Population and study’s methodology heterogenicity became clinical evolution of chronic spontaneous urticaria (CSU) highly variable. Objective: In a prospective cohort, we evaluated the different pathways of clinical evolution of CSU and identified possible risk factors. Methods: A total of 685 CSU patients (>12 years) were prospectively followed over 5 years. Diagnosis and follow-up of urticaria were based on medical evaluation and photographic records. Remission was defined as at least 6 months without symptoms (hives, angioedema, or pruritus) and medication. The follow-up included at least 2 visits per year, with photographic registration and clinical evaluation. Predefined clinical and paraclinical variables were included in the regression analyses. Results: We identified four clinical evolution pathways; The cumulative prevalence of remission at 5 years was 59.1%, recurrence was 17.1%, persistence was 11.6%, and chronic pruritus without hives or angioedema was 12.2%. The probability of persistence increased with hypothyroidism diagnosis (HR 0.425, 95% CI 0.290–0.621) and each point in the UAS7 (HR 0.931 95% CI 0.918– 0.945). Conclusion: Chronic urticaria has different evolutions. Disease activity and hypothyroidism predict persistence and remission. Recurrence and chronic pruritus phenotypes require further study to evaluate their causality and prognosis. | |
| dc.description | COL0059567 | |
| dc.format | 9 | |
| dc.format | application/pdf | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Elsevier | |
| dc.publisher | Grupo de Alergología Clínica y Experimental (GACE) | |
| dc.publisher | Atlanta, Estados Unidos | |
| dc.relation | World. Allergy. Organ. J. | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
| dc.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Urticaria Crónica | |
| dc.subject | Chronic Urticaria | |
| dc.subject | Recurrencia | |
| dc.subject | Recurrence | |
| dc.subject | Prurito | |
| dc.subject | Pruritus | |
| dc.title | Prospective analysis of clinical evolution in chronic urticaria: Persistence, remission, recurrence, and pruritus alone | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.type | http://purl.org/coar/resource_type/c_2df8fbb1 | |
| dc.type | https://purl.org/redcol/resource_type/ART | |
| dc.type | Artículo de investigación | |
