| dc.contributor | Rodas González, Juan David | |
| dc.contributor | Fernández Silva, Jorge Arturo | |
| dc.creator | Arroyave Sierra, Esteban | |
| dc.date | 2020-05-21T18:38:21Z | |
| dc.date | 2020-05-21T18:38:21Z | |
| dc.date | 2019 | |
| dc.date.accessioned | 2023-08-28T20:25:45Z | |
| dc.date.available | 2023-08-28T20:25:45Z | |
| dc.identifier | http://hdl.handle.net/10495/14517 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8479049 | |
| dc.description | ABSTRACT: Tick-borne rickettsial pathogens (TBRP) are important causes of infections in both dogs and humans. Dogs play an important role as a biological host for several tick species and can serve as sentinels for rickettsial infections. Our aim was to determine the presence of TBRP in dogs and in dog-associated ticks and their potential risk to human diseases in Medellin, Colombia. DNA for E. canis (16S rRNA and dsb) and A. platys (groEl) was detected in 17.6% (53/300) and 2.6% (8/300) of dogs, respectively. Antibodies against Ehrlichia spp. 82 (27.3%) and Anaplasma spp. 8 (2.6%) were detected in dogs. Antibody reactivity against both agents were found in 16 dogs (5.3%). Eight dogs showed antibody for Rickettsia spp. with titers that suggest 3 of them had a probable exposure to R. parkeri. Rhipicephalus sanguineus s.l. (178/193) was the main tick in dogs, followed by R. microplus (15/193). The minimum infection rates (MIR) in R. sanguineus were 11.8% for E. canis and 3.4% for A. platys. Our results indicate that E. canis and A. platys are the main TBRP infecting dogs and ticks in Medellin, Colombia. Interestingly, we found serological evidence of exposure in dogs for spotted fever group rickettsiae. | |
| dc.description | RESUMEN: Los patógenos rickettsiales transmitidos por garrapatas (TBRP) son causas importantes de infecciones tanto en perros como en humanos. Los perros juegan un papel importante como hospedadores biológicos de varias especies de garrapatas y pueden servir como centinelas para las infecciones por rickettsias. Nuestro objetivo fue determinar la presencia de TBRP en perros y garrapatas asociadas a perros y su riesgo potencial de enfermedades humanas en Medellín, Colombia. Se detectó ADN para E. canis (ARNr 16S y dsb) y A. platys (groEl) en el 17,6% (53/300) y el 2,6% (8/300) de los perros, respectivamente. Anticuerpos contra Ehrlichia spp. 82 (27,3%) y Anaplasma spp. 8 (2,6%) se detectaron en perros. Se encontró reactividad de anticuerpos contra ambos agentes en 16 perros (5,3%). Ocho perros mostraron anticuerpos contra Rickettsia spp. con títulos que sugieren que 3 de ellos tuvieron una probable exposición a R. parkeri. Rhipicephalus sanguineus s.l. (178/193) fue la principal garrapata en perros, seguida por R. microplus (15/193). Las tasas mínimas de infección (MIR) en R. sanguineus fueron 11,8% para E. canis y 3,4% para A. platys. Nuestros resultados indican que E. canis y A. platys son las principales TBRP que infectan a perros y garrapatas en Medellín, Colombia. Curiosamente, encontramos evidencia serológica de exposición en perros a las rickettsias del grupo de fiebre manchada. | |
| dc.format | 132 | |
| dc.format | application/pdf | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | CENTAURO | |
| dc.publisher | Medellín, Colombia | |
| dc.rights | Atribución-NoComercial-SinDerivadas 2.5 Colombia | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
| dc.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Rickettsiales | |
| dc.subject | Rhipicephalus sanguineus | |
| dc.subject | Ehrlichia | |
| dc.subject | Enfermedades por picaduras de garrapatas | |
| dc.subject | Tick-borne diseases in animals | |
| dc.subject | Perros | |
| dc.subject | Dogs | |
| dc.title | Tick-borne rickettsial pathogens in naturally infected dogs and dog-associated ticks and their role as sentinels of zoonotic rickettsial diseases in Medellin, Colombia | |
| dc.type | info:eu-repo/semantics/doctoralThesis | |
| dc.type | info:eu-repo/semantics/acceptedVersion | |
| dc.type | http://purl.org/coar/resource_type/c_db06 | |
| dc.type | https://purl.org/redcol/resource_type/TD | |
| dc.type | Tesis/Trabajo de grado - Monografía - Doctorado | |
