Placental Malaria in Colombia: Histopathologic Findings in Plasmodium vivax and P. falciparum Infections

dc.creatorCarmona Fonseca, Jaime
dc.creatorArango Flórez, Eliana María
dc.creatorMaestre Buitrago, Amanda Elena
dc.date2022-11-16T20:35:01Z
dc.date2022-11-16T20:35:01Z
dc.date2013
dc.date.accessioned2023-08-28T20:13:03Z
dc.date.available2023-08-28T20:13:03Z
dc.identifierCarmona-Fonseca J, Arango E, Maestre A. Placental malaria in Colombia: histopathologic findings in Plasmodium vivax and P. falciparum infections. Am J Trop Med Hyg. 2013 Jun;88(6):1093-101. doi: 10.4269/ajtmh.12-0363.
dc.identifier0002-9637
dc.identifierhttps://hdl.handle.net/10495/32101
dc.identifier10.4269/ajtmh.12-0363
dc.identifier1476-1645
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8475632
dc.descriptionABSTRACT: Studies on gestational malaria and placental malaria have been scarce in malaria-endemic areas of the Western Hemisphere. To describe the histopathology of placental malaria in Colombia, a longitudinal descriptive study was conducted. In this study, 179 placentas were studied by histologic analysis (112 with gestational malaria and 67 negative for malaria). Placental malaria was confirmed in 22.35%, 50.0% had previous infections, and 47.5% had acute infections. Typical malaria-associated changes were observed in 37%. The most common changes were villitis, intervillitis, deciduitis, increased fibrin deposition, increased syncytial knots, mononuclear (monocytes/macrophages and lymphocytes), polymorphonuclear cell infiltration, and trophozoites in fetal erythrocytes. No association was found between type of placental changes observed and histopathologic classification of placental malaria. The findings are consistent with those reported for placental malaria in other regions. Plasmodium vivax was the main parasite responsible for placental and gestational malaria, but its role in the pathogenesis of placental malaria was not conclusive.
dc.descriptionCOL0047449
dc.format9
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.publisherSalud y Comunidad
dc.publisherBaltimore, Estados Unidos
dc.relationAm. J. Trop. Med. Hyg.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.subjectColombia - epidemiología
dc.subjectColombia - epidemiology
dc.subjectEstudios de Casos y Controles
dc.subjectCase-Control Studies
dc.subjectEnfermedades Endémicas
dc.subjectEndemic Diseases
dc.subjectMalaria Falciparum
dc.subjectMalaria, Falciparum
dc.subjectMalaria Vivax
dc.subjectMalaria, Vivax
dc.subjectPlacenta
dc.subjectPlasmodium falciparum
dc.subjectPlasmodium vivax
dc.subjectEmbarazo
dc.subjectPregnancy
dc.titlePlacental Malaria in Colombia: Histopathologic Findings in Plasmodium vivax and P. falciparum Infections
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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