Human papillomavirus types in cases of squamous cell carcinoma of head and neck in Colombia

dc.creatorQuintero Martínez, Katherine
dc.creatorGiraldo Gómez, Gabriel Andrés
dc.creatorUribe Ríos, Mary Luz
dc.creatorBaena Zapata, Armando
dc.creatorLópez Urán, Carolina
dc.creatorÁlvarez Martínez, Efraín
dc.creatorSánchez Vásquez, Gloria Inés
dc.date2022-11-18T23:09:58Z
dc.date2022-11-18T23:09:58Z
dc.date2013
dc.date.accessioned2023-08-28T20:04:14Z
dc.date.available2023-08-28T20:04:14Z
dc.identifierQuintero K, Giraldo GA, Uribe ML, Baena A, Lopez C, Alvarez E, Sanchez GI. Human papillomavirus types in cases of squamous cell carcinoma of head and neck in Colombia. Braz J Otorhinolaryngol. 2013 May-Jun;79(3):375-81. doi: 10.5935/1808-8694.20130065.
dc.identifier1808-8694
dc.identifierhttps://hdl.handle.net/10495/32146
dc.identifier10.5935/1808-8694.20130065
dc.identifier1808-8686
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8473418
dc.descriptionABSTRACT: Estimating the type-specific prevalence of human papillomavirus (HPV) in head and neck cancer (HNSCC) is helpful in predicting the impact of HPV immunization. Objective: To estimate the overall prevalence, and gender and age-specific prevalence of HPV in HNSCC. Method: This cross sectional retrospective study was carried out in four pathology laboratories of Medellin, Colombia. HPV testing was performed by GP5+/6+ PCR-based RLB and HPV 16 and 18 type-specific PCR. Results: 175 primary HNSCC cases consecutively diagnosed between 1999 and 2008 with confirmed diagnosis and amplifiable DNA were included. Overall HPV prevalence was 18.9%. HPV was found in 23.9%, 17.5% and 13.3% of the oral cavity, larynx and oropharynx cases respectively. Among HPV positive cases, 82% were HPV 16 and 18% were HPV 18. No other HPV genotypes were identified. Most patients were males. Male patients were younger that their female counterparts, particularly in oral cavity cancer cases. Conclusion: HPV 16 and 18 genotypes were found in nearly 20% of HNSCC cases in Colombian patients. The impact of HPV vaccination for the prevention of HNSCC in this population deserves further evaluation.
dc.descriptionCOL0012328
dc.format7
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Otorrinolaringologia
dc.publisherInfección y Cáncer
dc.publisherSão Paulo, Brasil
dc.relationBraz. J. Otorhinolaryngol.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.subjectVacunas contra Papillomavirus
dc.subjectPapillomavirus Vaccines
dc.subjectNeoplasias Orofaríngeas
dc.subjectOropharyngeal Neoplasms
dc.subjectNeoplasias de Cabeza y Cuello
dc.subjectHead and Neck Neoplasms
dc.subjectInfecciones por Papillomavirus
dc.subjectPapillomavirus Infections
dc.subjectNeoplasias Laríngeas
dc.subjectLaryngeal Neoplasms
dc.subjectCarcinoma de Células Escamosas
dc.subjectCarcinoma, Squamous Cell
dc.subjectPapillomavirus Humano 16
dc.subjectHuman papillomavirus 16
dc.subjectPapillomavirus Humano 18
dc.subjectHuman papillomavirus 18
dc.titleHuman papillomavirus types in cases of squamous cell carcinoma of head and neck in Colombia
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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