| dc.creator | Santos, Rodrigo Pires dos | |
| dc.creator | Scheid, Karin Linck | |
| dc.creator | Willers, Denise Maria Cunha | |
| dc.creator | Goldani, Luciano Zubaran | |
| dc.date | 2010-05-05T04:15:54Z | |
| dc.date | 2008 | |
| dc.identifier | 1471-2334 | |
| dc.identifier | http://hdl.handle.net/10183/21556 | |
| dc.identifier | 000707810 | |
| dc.description | Background: Disseminated mycobacterial disease is an important cause of morbidity and mortality in patients with HIV-infection. Nonspecific clinical presentation makes the diagnosis difficult and sometimes neglected. Methods: We conducted a retrospective cohort study to compare the presentation of disseminated Mycobacterial tuberculosis (MTB) and non-tuberculous Mycobacterial (NTM) disease in HIV-positive patients from 1996 to 2006 in Brazil. Results: Tuberculosis (TB) was diagnosed in 65 patients (67.7%) and NTM in 31 (32.3%) patients. Patients with NTM had lower CD4 T cells counts (median 13.0 cells/mm3 versus 42.0 cells/mm3, P = 0.002). Patients with tuberculosis had significantly more positive acid-fast smears (48.0% vs 13.6%, P = 0.01). On chest X-ray, miliary infiltrate was only seen in patients with MTB (28.1% vs. 0.0%, P = 0.01). Pleural effusion was more common in patients with MTB (45.6% vs. 13.0%, P = 0.01). Abdominal adenopathy (73.1% vs. 33.3%, P = 0.003) and splenic hypoechoic nodules (38.5% vs. 0.0%, P = 0.002) were more common in patients with TB. Conclusion: Miliary pulmonary pattern on X-ray, pleural effusion, abdominal adenopathy, and splenic hypoechoic nodules were imaging findings associated with the diagnosis of tuberculosis in HIV-infected patients. Recognition of these imaging features will help to distinguish TB from NTM in AIDS patients with fever of unknown origin due to disseminated mycobacterial disease. | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.relation | BMC infectious diseases. London. Vol. 8, no. 24 (2008), p. 1-7 | |
| dc.rights | Open Access | |
| dc.subject | Infecções oportunistas relacionadas com a Aids | |
| dc.subject | Infecções por Mycobacterium | |
| dc.subject | Mycobacterium tuberculosis | |
| dc.title | Comparative radiological features of disseminated disease due to Mycobacterium tuberculosis vs non-tuberculosis mycobacteria among AIDS patients in Brazil | |
| dc.type | Artigo de periódico | |
| dc.type | Estrangeiro | |
