Mulinane-and Azorellane-type diterpenoids: A systematic review of their biosynthesis, chemistry, and pharmacology

dc.creatorAngel de Jesús Dzul Beh
dc.creatorANDRES HUMBERTO UC CACHON
dc.creatorJorge Borquez
dc.creatorluis loyola
dc.creatorLuis Manuel Peña Rodríguez
dc.creatorGLORIA MARIA MOLINA SALINAS
dc.date2020
dc.date.accessioned2023-07-21T19:19:27Z
dc.date.available2023-07-21T19:19:27Z
dc.identifierhttp://cicy.repositorioinstitucional.mx/jspui/handle/1003/1897
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7737449
dc.descriptionMulinane- and azorellane-type diterpenoids have unique tricyclic fused five-, six-, and seven-membered systems and a wide range of biological properties, including antimicrobial, antiprotozoal, spermicidal, gastroprotective, and anti-inflammatory, among others. These secondary metabolites are exclusive constituents of medicinal plants belonging to the Azorella, Laretia, and Mulinum genera. In the last 30 years, more than 95 mulinanes and azorellanes have been reported, 49 of them being natural products, 4 synthetics, and the rest semisynthetic and biotransformed derivatives. This systematic review highlights the biosynthetic origin, the chemistry, and the pharmacological activities of this remarkably interesting group of diterpenoids. 
dc.formatapplication/pdf
dc.languageeng
dc.relationinfo:eu-repo/semantics/datasetDOI/10.3390/biom10091333
dc.relationcitation:Dzul-Beh, A. D. J., Uc-Cachón, A. H., Bórquez, J., Loyola, L. A., Peña-Rodríguez, L. M., & Molina-Salinas, G. M. (2020). Mulinane-and Azorellane-type diterpenoids: A systematic review of their biosynthesis, chemistry, and pharmacology. Biomolecules, 10(9), 1333.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.sourceBiomolecules, 10(9), 1333, 2020.
dc.subjectinfo:eu-repo/classification/Autores/MULINANE
dc.subjectinfo:eu-repo/classification/Autores/AZORELLANE
dc.subjectinfo:eu-repo/classification/Autores/DITERPENOIDS
dc.subjectinfo:eu-repo/classification/Autores/ANTIMYCOBACTERIAL
dc.subjectinfo:eu-repo/classification/Autores/ANTIULCER
dc.subjectinfo:eu-repo/classification/cti/2
dc.subjectinfo:eu-repo/classification/cti/24
dc.subjectinfo:eu-repo/classification/cti/2415
dc.subjectinfo:eu-repo/classification/cti/241502
dc.subjectinfo:eu-repo/classification/cti/241502
dc.titleMulinane-and Azorellane-type diterpenoids: A systematic review of their biosynthesis, chemistry, and pharmacology
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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