Antibacterial activity of a glass ionomer cement doped with copper nanoparticles

dc.creatorDAVID ALEJANDRO AGUILAR PEREZ
dc.creatorROSSANA FARIDE VARGAS CORONADO
dc.creatorJOSE MANUEL CERVANTES UC
dc.creatorNAYELI RODRIGUEZ FUENTES
dc.creatorConrado Aparicio
dc.creatorCRISTIAN COVARRUBIAS CERDA
dc.creatorMARCO ANTONIO ALVAREZ PEREZ
dc.creatorVICTOR IRAHUEN GARCIA PEREZ
dc.creatorMIRYAM MARTINEZ HERNANDEZ
dc.creatorJUAN VALERIO CAUICH RODRIGUEZ
dc.date2020
dc.date.accessioned2023-07-21T19:19:22Z
dc.date.available2023-07-21T19:19:22Z
dc.identifierhttp://cicy.repositorioinstitucional.mx/jspui/handle/1003/1853
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7737405
dc.descriptionCopper nanoparticles (NCu) were synthetized and added to commercial glass ionomer cement, to evaluate in vitro its antibacterial activity against oral cavity strains. The NCu were synthesized by copper acetate reduction with L-ascorbic acid and characterized by FTIR, Raman, XPS, XRD and TEM. Then, commercial glass ionomer cement (GIC) was modified (MGIC) with various concentrations of NCu and physicochemically characterized. Cell viability was tested against human dental pulp fibroblasts (HDPFs) by Alamar-Blue assay and antibacterial test was performed against S. mutans and S. sanguinis by colony forming unit (CFU) growth method. Synthesized NCu rendered a mixture of both metallic copper and cuprous oxide (Cu2O). HDPF viability reduces with exposure time to the extracts (68-72% viability) and MGIC with 2-4 wt% NCu showed antimicrobial activity against the two tested strains.
dc.formatapplication/pdf
dc.languageeng
dc.relationinfo:eu-repo/semantics/datasetDOI/doi:10.4012/dmj.2019-046
dc.relationcitation:Aguilar-Perez D, Vargas-Coronado R, Cervantes-Uc JM, Rodriguez-Fuentes N, Aparicio C, Covarrubias C, Alvarez-Perez M, Garcia-Perez V, Martinez-Hernandez M, Cauich-Rodriguez JV. Antibacterial activity of a glass ionomer cement doped with copper nanoparticles. Dent Mater J. 2020 Jun 5;39(3):389-396. doi: 10.4012/dmj.2019-046. Epub 2020 Mar 24. PMID: 32213765.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.sourceDent Mater J. 2020 Jun 5;39(3):389-396. doi: 10.4012/dmj.2019-046. Epub 2020 Mar 24. PMID: 32213765.
dc.subjectinfo:eu-repo/classification/Autores/ANAEROBIA BACTERIA
dc.subjectinfo:eu-repo/classification/Autores/BIOMATERIAL
dc.subjectinfo:eu-repo/classification/Autores/DENTAL CEMENT
dc.subjectinfo:eu-repo/classification/Autores/FIBROBLAST
dc.subjectinfo:eu-repo/classification/Autores/METAL NANOPARTICLE
dc.subjectinfo:eu-repo/classification/cti/7
dc.subjectinfo:eu-repo/classification/cti/33
dc.subjectinfo:eu-repo/classification/cti/3312
dc.subjectinfo:eu-repo/classification/cti/331208
dc.subjectinfo:eu-repo/classification/cti/331208
dc.titleAntibacterial activity of a glass ionomer cement doped with copper nanoparticles
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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