Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization

dc.creatorPAOLA IVETH CAMPA SIQUEIROS
dc.creatorTomás J. Madera-Santana
dc.creatorJesús Fernando Ayala Zavala
dc.creatorJAIME LOPEZ CERVANTES
dc.creatorMARIA MONICA CASTILLO ORTEGA
dc.creatorPedro Jesús Herrera Franco
dc.date2020
dc.date.accessioned2023-07-21T19:19:19Z
dc.date.available2023-07-21T19:19:19Z
dc.identifierhttp://cicy.repositorioinstitucional.mx/jspui/handle/1003/1832
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7737384
dc.descriptionElectrospun nanofibers from gelatin (G), chitosan (CS), and chitosan-polyvinyl alcohol (CS-PVA) were developed by electrospinning process. Mechanical properties were determined by the tensile test, the elastic modulus values of the nanofibers were G (15.418-34.34 MPa) and CS-PVA (17.44-126.427 MPa). The morphological characterization by SEM revealed that the systems with 15% G and 6% CS-PVA showed morphological homogeneity. Structural characterization by FTIR indicated an interaction among some functional groups of the component. Thermal analysis by DSC and TGA showed degradation temperatures for G (330 °C), CS (210 °C to 370 °C), and PVA (310 °C to 420 °C). The contact angles values denoted the hydrophilic nature of the material. Finally, the antimicrobial assay proved that both 15% G and 7% PVA on the CS-PVA system presented the best antimicrobial effect. The results indicate that the electrospun nanofibers fabricated with G or CS-PVA can be used as wound healing dressings.
dc.formatapplication/pdf
dc.languageeng
dc.relationinfo:eu-repo/semantics/datasetDOI/https://doi.org/10.1590/0104-1428.07919
dc.relationcitation:Campa-Siqueiros, P., Madera-Santana, T. J., Ayala-Zavala, J. F., López-Cervantes, J., Castillo-Ortega, M. M., & Herrera-Franco, P. J. (2020). Nanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization. Polímeros, 30(1).
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.sourcePolímeros, 30(1), 2020
dc.subjectinfo:eu-repo/classification/Autores/CHITOSAN
dc.subjectinfo:eu-repo/classification/Autores/ELECTROSPINNING
dc.subjectinfo:eu-repo/classification/Autores/GELATIN
dc.subjectinfo:eu-repo/classification/Autores/PVA
dc.subjectinfo:eu-repo/classification/Autores/WOUND DRESSING
dc.subjectinfo:eu-repo/classification/cti/7
dc.subjectinfo:eu-repo/classification/cti/33
dc.subjectinfo:eu-repo/classification/cti/3312
dc.subjectinfo:eu-repo/classification/cti/331208
dc.subjectinfo:eu-repo/classification/cti/331208
dc.titleNanofibers of gelatin and polivinyl-alcohol-chitosan for wound dressing application: fabrication and characterization
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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