| dc.creator | Dini, Cecilia | |
| dc.creator | Islan, Germán Abel | |
| dc.creator | Urraza, Patricio José de | |
| dc.creator | Castro, Guillermo Raúl | |
| dc.date | 2012 | |
| dc.date | 2023-05-19T16:06:21Z | |
| dc.date.accessioned | 2023-07-15T10:35:54Z | |
| dc.date.available | 2023-07-15T10:35:54Z | |
| dc.identifier | http://sedici.unlp.edu.ar/handle/10915/153287 | |
| dc.identifier | issn:1616-5195 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/7492474 | |
| dc.description | Phage therapy by oral administration requires enhanced resistance of phages to the harsh gastric conditions. The aim of this work is the microencapsulation of phages in natural biopolymeric matrices as a protective barrier against the gastric environment. Alginate and pectin are used as base polymers. Further emulsification with oleic acid or coating with a different biopolymer is also studied. Emulsified pectin shows the maximum encapsulation efficiency and the highest protection against acidity, leaving more than 10³ active phages after 30 min exposure at pH¼1.6, and protects phage from pepsin activity (4.2mgmL⁻¹). Non-encapsulated phages are fully inactivated at pH¼1.6 or with pepsin (0.5mgmL⁻¹) after 10 min. | |
| dc.description | Centro de Investigación y Desarrollo en Fermentaciones Industriales | |
| dc.format | application/pdf | |
| dc.format | 1200–1208 | |
| dc.language | en | |
| dc.rights | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
| dc.rights | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | |
| dc.subject | Biología | |
| dc.subject | Biocontrol | |
| dc.subject | Biological applications of polymers | |
| dc.subject | Biopolymers | |
| dc.subject | Microencapsulation | |
| dc.subject | Phages | |
| dc.title | Novel biopolymer matrices for microencapsulation of phages: enhanced protection against acidity and protease activity | |
| dc.type | Articulo | |
| dc.type | Articulo | |
