Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas

dc.creatorBadrán, Amado F.
dc.creatorNash, R. E.
dc.creatorEchave Llanos, Julián Miguel
dc.date1971
dc.date2022-08-23T12:51:20Z
dc.date.accessioned2023-07-15T04:52:50Z
dc.date.available2023-07-15T04:52:50Z
dc.identifierhttp://sedici.unlp.edu.ar/handle/10915/140861
dc.identifierissn:0340-0336
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7471237
dc.descriptionAn electron microscopic analysis was performed on the pars distalis of the hypophysis of mice bearing transplanted hepatomas. Normal mice served as controls. In animals bearing a fast growing as well as in those bearing a slow growing hepatoma, the STH cells presented changes indicating increased release and synthesis of its secretory product. These changes can be summarized as follows: 1) Increased number of granuledepleted STH cells which were very irregular in size and shape. 2) Very irregular and sometimes bizarre nuclei. 3) Plasma membranes irregular and convoluted. 4) Increased quantity of endoplasmic reticulum which appeared sometimes dilated and contained material of varying electron density. 5) Abundant, irregular and frequently ramified mitochondria. 6) Hypertrophic Golgi system with increased number of microvesicles. 7) Increased number of large lysosomes of different type. 8) Increased number of fat droplets.
dc.descriptionFacultad de Ciencias Médicas
dc.formatapplication/pdf
dc.format525-531
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by/4.0/
dc.rightsCreative Commons Attribution 4.0 International (CC BY 4.0)
dc.subjectMedicina
dc.subjectBiología
dc.subjectHypophysis
dc.subjectMouse
dc.subjectPars distalis
dc.subjectSTH cells
dc.subjectHepatomas
dc.titleUltrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
dc.typeArticulo
dc.typeArticulo


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