Effect of hydromechanical forces on the production of filamentous haemagglutinin and pertussis toxin of Bordetella pertussis

dc.creatorRodríguez, María Eugenia
dc.creatorSamo, Analia L.
dc.creatorHozbor, Daniela Flavia
dc.creatorYantorno, Osvaldo Miguel
dc.date1993
dc.date2022-07-11T19:46:45Z
dc.date.accessioned2023-07-15T04:49:38Z
dc.date.available2023-07-15T04:49:38Z
dc.identifierhttp://sedici.unlp.edu.ar/handle/10915/139310
dc.identifierissn:0169-4146
dc.identifierissn:1476-5535
dc.identifierissn:1367-5435
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7471032
dc.descriptionThe production of Bordetella pertussis extracytoplasmic filamentous haemagglutinin (FHA) and pertussis toxin (PT) in a bioreactor under stirring conditions was studied in order to investigate the effect of hydromechanical forces on yields of both antigens. It was shown that FHA loses its haemagglutinin activity when the power transmitted by the agitator and the aerator per unit volume increases, whereas PT production is not affected. The loss of FHA activity can be explained by the action of shear forces on the filamentous structure of this antigen.
dc.descriptionCentro de Investigación y Desarrollo en Fermentaciones Industriales
dc.formatapplication/pdf
dc.format103-108
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by/4.0/
dc.rightsCreative Commons Attribution 4.0 International (CC BY 4.0)
dc.subjectQuímica
dc.subjectFísica
dc.subjectBordetella pertussis
dc.subjectFilamentous haemagglutinin
dc.subjectPertussis toxin
dc.subjectProduction
dc.subjectShear stress
dc.subjectBioreactor
dc.titleEffect of hydromechanical forces on the production of filamentous haemagglutinin and pertussis toxin of Bordetella pertussis
dc.typeArticulo
dc.typeArticulo


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