Metastatic dissemination with special emphasis on breast cancer cutaneous metastases

dc.creatorLuna, Amalia
dc.creatorSegal-Eiras, Amada
dc.creatorCroce, María Virginia
dc.date2015
dc.date2021-11-04T16:21:17Z
dc.date.accessioned2023-07-15T03:59:49Z
dc.date.available2023-07-15T03:59:49Z
dc.identifierhttp://sedici.unlp.edu.ar/handle/10915/127763
dc.identifierhttps://pmr.safisiol.org.ar/wp-content/uploads/2022/07/vol_8_3.pdf
dc.identifierissn:1669-5402
dc.identifierissn:1669-5410
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7467854
dc.descriptionMetastatic development is a complex, multistage process involving modulation of cell phenotype, cell migration, and dynamic homeotypic as well as heterotypic cell-cell interactions. In breast cancer, MUC1 mucin has been emerging as a key molecule involved in metastasis. MUC1 is a large transmembrane glycoprotein expressed by mammary normal epithelial cells but it is overexpressed and underglycosylated in cancer cells. Cutaneous metastasis is a neoplastic lesion localized at the dermis or subcutaneous cellular tissue, which is not contiguous to the primary tumor, with an overall incidence of 5.3%. The most common tumor to metastasize to the skin is breast cancer with an incidence of 24%. We present a minireview on metastatic dissemination with special emphasis on breast cancer cutaneous metastases and the role that MUC1 plays on it.
dc.descriptionSociedad Argentina de Fisiología
dc.formatapplication/pdf
dc.format23-32
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by/4.0/
dc.rightsCreative Commons Attribution 4.0 International (CC BY 4.0)
dc.subjectCiencias Médicas
dc.subjectmetastases
dc.subjectcutaneous metastases
dc.subjectbreast cancer
dc.subjectMUC1
dc.titleMetastatic dissemination with special emphasis on breast cancer cutaneous metastases
dc.typeArticulo
dc.typeRevision


Este ítem pertenece a la siguiente institución