Glutathione-complexed iron–sulfur clusters: reaction intermediates and evidence for a template effect promoting assembly and stability

dc.creatorQi, Wenbin
dc.creatorLi, Jingwei
dc.creatorChain, Cecilia Yamil
dc.creatorPasquevich, Gustavo Alberto
dc.creatorPasquevich, Alberto Felipe
dc.creatorCowan, J. A.
dc.date2013-07-18
dc.date2021-10-27T17:01:47Z
dc.date.accessioned2023-07-15T03:49:30Z
dc.date.available2023-07-15T03:49:30Z
dc.identifierhttp://sedici.unlp.edu.ar/handle/10915/127388
dc.identifierissn:1364-548X
dc.identifierissn:1359-7345
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7467195
dc.descriptionAssembly and stabilization of a glutathione-complexed [2Fe–2S] cluster is promoted by aggregation of glutathione. The cluster core selects the tetramer species from a collection of equilibrating solution aggregate species, and in turn the core is stabilized toward hydrolytic degradation. Studies of glutathione derivatives, in combination with mass spectrometric and Mossbauer investigations provide insight on reaction intermediates during formation of [2Fe–2S](GS)₄²⁻.
dc.descriptionFacultad de Ciencias Exactas
dc.formatapplication/pdf
dc.format6313-6315
dc.languageen
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rightsCreative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.subjectQuímica
dc.subjectReaction intermediate
dc.subjectCluster (physics)
dc.subjectMass spectrometry
dc.subjectChemistry
dc.subjectCombinatorial chemistry
dc.subjectTetramer
dc.subjectMolecule
dc.subjectSulfur
dc.subjectGlutathione
dc.subjectCrystallography
dc.subjectTurn (biochemistry)
dc.titleGlutathione-complexed iron–sulfur clusters: reaction intermediates and evidence for a template effect promoting assembly and stability
dc.typeArticulo
dc.typePreprint


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