| dc.creator | De Sousa Fontes, Aderito | |
| dc.date | 2023-03-21T17:45:59Z | |
| dc.date | 2023-03-21T17:45:59Z | |
| dc.date | 2021-12-03 | |
| dc.date.accessioned | 2023-07-13T15:11:31Z | |
| dc.date.available | 2023-07-13T15:11:31Z | |
| dc.identifier | De Sousa Fontes, Aderito (2021). Clínica, endoscopia, imagenología e histopatología en el manejo de los Papilomas Rinosinusales. Tesis Doctoral presentada para optar al Título de Doctor en Ciencias de la Salud. Tutor: Dr. Bianco C, Nicolas | |
| dc.identifier | http://hdl.handle.net/10872/22057 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/7422562 | |
| dc.description | Todos los pacientes fueron evaluados endoscopica, imagenologicamente con TC y RMN con contraste e histopatologicamente y los resultados fueron correlacionados minuciosamente. Todos los pacientes con
PRS presentaron polipos nasales endoscopicamente e imagenes tomograficas de opacificacion coincidentes con el hallazgo endoscopico. La Hiperostosis focal fue observada en el 79% de los casos y la erosion de paredes oseas se aprecio en el 84% de los casos. Las imagenes con patron contorneado cerebriforme por
RMN fueron identificadas en el 86% de los estudios.
Los reportes histopatologicos senalados fueron de 67% para PI, el 30% para PF y 3% para PO. El 33% de los pacientes tuvieron enfermedad recurrente y el 3% presentaron malignidad asociada.
La correlacion de los hallazgos endoscopicos e imagenologicos mostraron un nivel de exactitud diagnostica para los PRS con una media global promedio del
90%. Se analizaron estadisticamente los niveles de prediccion, probabilidad de influencia y fiabilidad diagnostica para este tipo de neoplasias a traves de una
EIS correlativa cuantitativa inedita, como herramienta de orientacion diagnostica. Conclusiones: La correlacion exhaustiva de los estudios endoscopicos,
imagenologicos e histopatologicos fueron decisivas para su diagnostico oportuno y permitieron identificar lesiones asintomaticas de manera significativa. La experiencia analizada propicio la elaboracion de un algoritmo de manejo integralde estas neoplasias | |
| dc.description | To evaluate the correlation between endoscopic, imaging and histopathological findings in patients with sinonasal papillomas (SP), in a private tertiary otolaryngology care center.
Material and methods: 103 patients with SP were studied over 28 years, evaluating demographic data, clinical characteristics, endoscopic, radiological, and histopathological findings, anatomical origin, extent of the disease, treatments performed, recurrences, and long-term follow-up.
Results: All patients were studied endoscopically, CT (computed tomography), contrast MRI (nuclear magnetic resonance), and histopathologically and the results were carefully correlated. All patients with SP presented nasal polyps endoscopically and tomographic images of opacification coincident with the endoscopic finding. Focal hyperostosis was observed in 79% of patients and erosion of bony walls was observed in 84% of patients. convoluted cerebriform pattern by contrast MRI were identified in 86% of cases. Histopathological reports were 67% to IP (inverted papilloma), 30% to FP (fungiform papilloma) and 3% OP (oncocitic papilloma). 33% of the patients had recurrent disease and 3% had associated malignancy.
The correlation of the endoscopic and imaging findings showed an accuracy levels of diagnostic for SP with a global mean of 90%. Levels of prediction, probability of influence and diagnostic reliability for this type of neoplasms were statistically analyzed through an unprecedented quantitative correlative EIS, as
a tool for diagnostic guidance.
Conclusions: Exhaustive correlation of the endoscopic, imaging and histopathological findings were decisive for its timely diagnosis and allowed to identify asymptomatic lesions significantly. The experience analyzed led to the development of an algorithm for the comprehensive management of these
neoplasms | |
| dc.language | es | |
| dc.subject | Pólipos nasales | |
| dc.subject | Neoplasia nasosinusal | |
| dc.subject | Papiloma rinosinusal | |
| dc.subject | Papiloma Invertido | |
| dc.subject | Papiloma Fungiforme | |
| dc.subject | Papiloma Oncocítico | |
| dc.subject | Faculta de Medicina | |
| dc.subject | Coordinación de Postgrado | |
| dc.title | Clínica, endoscopia, imagenología e Histopatología en el manejo de los Papilomas Rinosinusales. | |
| dc.type | Thesis | |
