Estudo dos aspectos radiográficos dos linfomas e leucemias em maxila e mandíbula

Abstract

Objective: To investigate the radiographic features of lymphomas and leukemias in the jaws. Study Design: A systematic review was carried out in the electronic databases Pubmed, Web of Science and Scopus using specific search strategies. Inclusion criteria comprised articles that provided periapical, panoramic or computed tomography (CT) images for individual cases and diagnoses of lymphoma/leukemia confirmed by immunohistochemistry. Three experts evaluated and described individually the images and the quality of the radiographic exams. Results: From 1079 reports screened, 129 cases containing 88 tomographic, 77 panoramic and 26 periapical exams were selected, most of them classified as excellent (54%). Diffuse large B-cell lymphomas NOS (DLBCL), Burkitt lymphoma, leukemic infiltration, T/NK-cell lymphoma and plasmablastic lymphoma were the most common subtypes. Involved teeth presented mobility in 37.2% of the cases and a provisional diagnosis of inflammatory/infectious dental disease was considered in 49.2% of the patients. Most cases were radiolucent in plain exams and conventional CT exams were available for 76% of the cases, with hypodense aspect and ill-defined borders. Periosteal reactions were uncommon. Conclusion: Lymphoma/leukemia with gnathic bone destruction are usually of high-grade subtypes and rarely present periosteal reactions.