dc.contributorMurray Herrera, Victor Manuel
dc.creatorGonzales Vera, Ricardo Alonso
dc.creatorSeemann, Felicia
dc.creatorLamy, Jérôme
dc.creatorArvidsson, Per M.
dc.creatorHeiberg, Einar
dc.creatorPeters, Dana C.
dc.date.accessioned2021-08-17T21:42:16Z
dc.date.available2021-08-17T21:42:16Z
dc.date.created2021-08-17T21:42:16Z
dc.date.issued2021-06-19
dc.identifierGonzales, R. A., Seemann, F., Lamy, J., Arvidsson, P. M., Heiberg, E., Murray, V. y Peters, D. C. Automated left atrial time-resolved segmentation in MRI long-axis cine images using active contours. BMC Med Imaging 21, 101 (2021). https://doi.org/10.1186/s12880-021-00630-3
dc.identifier1471-2342
dc.identifierhttps://hdl.handle.net/20.500.12815/244
dc.identifierhttps://doi.org/10.1186/s12880-021-00630-3
dc.identifierBMC Medical Imaging
dc.description.abstractBackground: Segmentation of the left atrium (LA) is required to evaluate atrial size and function, which are important imaging biomarkers for a wide range of cardiovascular conditions, such as atrial fbrillation, stroke, and diastolic dysfunction. LA segmentations are currently being performed manually, which is time-consuming and observer-dependent. Methods: This study presents an automated image processing algorithm for time-resolved LA segmentation in cardiac magnetic resonance imaging (MRI) long-axis cine images of the 2-chamber (2ch) and 4-chamber (4ch) views using active contours. The proposed algorithm combines mitral valve tracking, automated threshold calculation, edge detection on a radially resampled image, edge tracking based on Dijkstra’s algorithm, and post-processing involving smoothing and interpolation. The algorithm was evaluated in 37 patients diagnosed mainly with paroxysmal atrial fibrillation. Segmentation accuracy was assessed using the Dice similarity coefcient (DSC) and Hausdorf distance (HD), with manual segmentations in all time frames as the reference standard. For inter-observer variability analysis, a second observer performed manual segmentations at end-diastole and end-systole on all subjects. Results: The proposed automated method achieved high performance in segmenting the LA in long-axis cine sequences, with a DSC of 0.96 for 2ch and 0.95 for 4ch, and an HD of 5.5 mm for 2ch and 6.4 mm for 4ch. The manual inter-observer variability analysis had an average DSC of 0.95 and an average HD of 4.9 mm. Conclusion: The proposed automated method achieved performance on par with human experts analyzing MRI images for evaluation of atrial size and function.
dc.languageeng
dc.publisherUniversidad de Ingeniería y Tecnología
dc.publisherBioMed Central
dc.publisherPE
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.sourceRepositorio Institucional UTEC
dc.sourceUniversidad de Ingeniería y Tecnología - UTEC
dc.subjectActive contours
dc.subjectCardiovascular imaging
dc.subjectMagnetic resonance imaging
dc.subjectLeft atrium
dc.subjectSegmentation
dc.titleAutomated left atrial time-resolved segmentation in MRI long-axis cine images using active contours
dc.typeinfo:eu-repo/semantics/bachelorThesis


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