Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon

dc.creatorTauchen, Jan
dc.creatorBortl, Ludvik
dc.creatorHuml, Lukas
dc.creatorMiksatkova, Petra
dc.creatorDoskocil, Ivo
dc.creatorMarsik, Petr
dc.creatorPanduro Villegas, Pablo Pedro
dc.creatorBendezu Flores, Ymber
dc.creatorVan Damme, Patrick
dc.creatorLojka, Bohdan
dc.creatorHavlik, Jaroslav
dc.creatorLapcik, Oldrich
dc.creatorKokoska, Ladislav
dc.date.accessioned2020-10-03T01:22:17Z
dc.date.accessioned2023-05-24T15:01:11Z
dc.date.available2020-10-03T01:22:17Z
dc.date.available2023-05-24T15:01:11Z
dc.date.created2020-10-03T01:22:17Z
dc.date.issued2016-06-14
dc.identifierTauchen, J.; Bortl, L.; Huml, L.; Miksatkova, P.; Doskocil, I.; Marsik, P.; Panduro, P.; Bendezu, Y.; Van Damme, P.; Lojka, B.; Havlik, J.; Lapcik, O.; Kokoska, L. (2016). Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon. Revista Brasileira de Farmacognosia Volume 26, Issue 6, Pages 728-737. doi: 10.1016/j.bjp.2016.03.016
dc.identifierhttp://repositorio.inia.gob.pe/handle/20.500.12955/1143
dc.identifierRevista Brasileira de Farmacognosia
dc.identifierhttp://dx.doi.org/10.1016/j.bjp.2016.03.016
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/6440555
dc.description.abstractAmong 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 μg/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 μg/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases.
dc.languageeng
dc.publisherEl Sevier
dc.publisherBrasil
dc.relationRevista Brasileira de Farmacognosia Volume 26, Issue 6, November–December 2016, Pages 728-737
dc.relationhttp://dx.doi.org/10.1016/j.bjp.2016.03.016
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceInstituto Nacional de Innovación Agraria
dc.sourceRepositorio Institucional - INIA
dc.subjectAntioxidant
dc.subjectAnticarcinogenic
dc.subjectPhenolic compounds
dc.subjectPlant extracts
dc.titlePhenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
dc.typeinfo:eu-repo/semantics/article


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