| dc.description.abstract | Urinary tract infection (UTI) is caused by the invasion of microorganisms in the urothelial
epithelium, which overcome the host innate and acquired immunity barriers. This syndrome
depends both on the characteristics of uropathogens (susceptibility, species, etc.) and on the
host (age, sex, immunodepression). Is mainly caused by gram-negative Enterobacteriaceae
and several of them produce extended-spectrum beta-lactamases (ESBLs), such as the
genus Escherichia spp., Klebsiella spp. and Proteus spp., which confer them resistance to
antibiotics like penicillin, cephalosporins and aztreonam. The objective of the research was to
determine the frequency of Enterobacteriaceae producing extended-spectrum betalactamase,
isolated from urine cultures of patients in Monte Sinai Hospital in 2020-2021. A
descriptive and cross-sectional study was conducted, the sample was purposive and nonprobabilistic.
The data were analyzed by means of simple and crossed frequency tables,
created in the SPSS and Microsoft Excel statistical software. The results obtained were 3,798
positive urine cultures, the most frequently isolated uropathogens were Enterobacteriaceae
with 60.9% (n=2,314), of which 15% (n=349) presented BLEE resistance. The main BLEEproducing
bacilli were Escherichia coli (90.8%; n=317), Klebsiella pneumoniae (8.6%; n=30)
and Proteus mirabilis (0.6% n=2). In conclusion, Escherichia coli was the uropathogen with
the highest prevalence of BLEE at Mount Sinai Hospital, predominantly in females, in patients
over 60 years of age and in outpatient services. | |
