ARTÍCULO
The role of microbiota in ALS pathogenesis and progression: a literature review
Autor
Cuji Galarza, Wendy Dayanna
Cabrera Jara, Paul Sebastian
Abril Ortiz, Pedro Jose
Machado Orellana, Maria Gabriela
Orellana Paucar, Adriana Monserrath
Institución
Resumen
Introduction
In recent years there has been a great interest in investigating the intestinal microbiota and its role both in healthy people and in various pathologies. This has given rise to the concept of the gut-brain axis, where the relationship between the microbiota and neurological pathologies, such as amyotrophic lateral sclerosis, whose pathogenesis is still unclear, is studied
Development
This review provides an overview of the role of the gut microbiota in the pathogenesis and progression of amyotrophic lateral sclerosis.
Conclusions
There is evidence of the role of the modulation exerted by the microbiota on the immune state as well as its direct effects on the CNS.