Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario

dc.creatorPerez, Sandra
dc.creatorManrique, Julieta
dc.creatorMoran, Pedro
dc.creatorRomeo, Florencia
dc.creatorAngelini, Hernán Pablo
dc.creatorLeunda, Maria Rosa
dc.creatorPereyra, Susana Beatriz
dc.creatorSpetter, Lucas Maximiliano
dc.creatorGonzalez Altamiranda, Erika
dc.creatorOdeon, Anselmo Carlos
dc.creatorJones, Leandro
dc.creatorVerna, Andrea Elizabeth
dc.date.accessioned2020-08-20T12:20:41Z
dc.date.accessioned2023-03-15T14:05:23Z
dc.date.available2020-08-20T12:20:41Z
dc.date.available2023-03-15T14:05:23Z
dc.date.created2020-08-20T12:20:41Z
dc.date.issued2020-04
dc.identifier1573-4978
dc.identifier0301-4851
dc.identifierhttps://doi.org/10.1007/s11033-020-05449-9
dc.identifierhttp://hdl.handle.net/20.500.12123/7744
dc.identifierhttps://link.springer.com/article/10.1007/s11033-020-05449-9
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/6210819
dc.description.abstractBovine herpevsirus 4 (BoHV-4) is a gammaherpesvirus that has been associated with different clinical conditions in cattle. In Argentina, BoHV-4 was detected in diverse bovine samples. The aim of this study was to analyze the genetic relationship of 48 field BoHV-4 strains isolated from cattle in Argentina. According to thymidine kinase (tk) gene sequences, BoHV-4 isolates belong to genotypes 1, 2 and 3. Phylogenetic analyses confirmed the presence of the three previously described viral genotypes. However, some of the studied isolates presented conflicting phylogenetic signals between the studied markers. This suggests a complex evolutionary background, that is a history of recombination, incomplete lineage sorting (deep coalescence) or a combination of these, which requires further study. These potential events make difficult the diagnosis of BoHV-4 from clinical samples of cattle and may pose a significant problem for the control of the virus in the herds.
dc.languageeng
dc.publisherSpringer Nature
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourceMolecular Biology Reports 47 : 4905–4909 (2020)
dc.subjectGanado Bovino
dc.subjectHerpes Virus Bovino
dc.subjectFilogenia
dc.subjectArgentina
dc.subjectCattle
dc.subjectBovine Herpesvirus
dc.subjectPhylogeny
dc.titleGenetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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